The aim of this study was to analyze the sociodemographic, epidemiological, clinical and laboratory-related factors associated with the abandonment of antiretroviral therapy (ART) and the clinical and laboratory follow-up data of patients with human immunodeficiency virus (HIV) infection. This retrospective case-control study was conducted in the Reference Centre for Sexually Transmitted Diseases AIDS of Campinas-SP, from 2010 to 2015, with 50 cases of treatment abandonment and 66 cases with treatment and regular follow-ups. After univariate analysis, the multiple logistic regression model was adjusted using the cases, controls and covariables of interest. Being black/brownskinned, unemployed and heterosexual, and having a smoking habit were associated with abandonment, while a higher level of education and the presence of a multi-professional healthcare team predicted adherence to ART and follow-up. Hence, ART abandonment and follow-up are associated with unfavorable socioeconomic indicators and not with the integral care to patients. Our results may help in the identification of patients at a risk of abandoning treatment and follow-up, and formulation of prevention strategies for the same.
IC 95%: 0,04 -0,91) apareceram como fatores preditores do seguimento e uso de TARV. Variáveis associadas à vulnerabilidade socioeconômica associaram-se positivamente ao abandono enquanto maior escolaridade e o atendimento do paciente por equipe multiprofissional parecem prevenir a sua ocorrência.Palavras chave: HIV, Síndrome de Imunodeficiência Adquirida, adesão à medicação, terapia antirretroviral de alta atividade.
IntroductionThe objective of the study was to identify and analyse the sociodemographic, epidemiological, clinical and laboratory factors associated with treatment abandonment and follow-up among PLHA. MethodsThis is a retrospective case control study of a sample of medical records of adult patients with HIV who use a referral centre for STD in municipality of Campinas-SP, Brazil. Cases were patients without antiretroviral withdrawal at the pharmacy for 365 days or more, obtained from the Logistic Control System of Medicines in July 2015, (n=50). For controls group, 100 adult patients adhering to ART were randomly selected for 365, and 58 meet the criteria, from March 2014 to March 2015. After the univariate analysis of the data, a multiple logistic regression model was adjusted considering cases, controls and covariates of interest. ResultsThe variables that favoured the abandonment of follow-up and treatment were: black/brown referred colour (OR=6.54, 95% CI: 1.48–28.88), being unemployed (OR=6.38, 95% CI: 1.61–25.35), being heterosexual (OR=6.94, 95% CI: 1.18 40.97) and being smoker (OR=10.39, 95% CI: 2.59–41.69). Higher education (OR=0.05, 95% CI: 0.00–0.46) and to be attended by multi professional team (OR=0.19, 95% CI: 0.04–0.96) appeared as protective factors of abandonment. ConclusionThe abandonment of follow-up and treatment among the patients from STD/HIV referred centre in Campinas were positively associated with socioeconomic precariousness. Access to the multiprofessional team was a protective factor to prevent abandonment of ART in the study population.
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