The use of the task-evoked pupillary responses (TEPRs) methodology is emerging in the psycholinguistics literature, as a sensitive, reliable and dynamic psychophysiological measure of the cognitive effort produced by various aspects of language processing. This preliminary study aimed to assess the functionality and effectiveness of a TEPRs design for measuring the cognitive effort required for the processing and spontaneous (non-explicitly prompted) short-term retention of novel phonological forms presented auditorily. Twenty-four young adult participants (aged 19–28 years, M = 20.3, SD = 2.13) were auditorily presented with a series of pseudowords differing in their number of syllables and their syllabic complexity. Then, they were asked to produce a response to a delayed pseudoword–color matching task aimed to induce the short-term retention of the novel forms. Results on the size and timing of the TEPRs reveal a significant pupillary activation, starting immediately after the presentation of the auditory stimuli, peaking at 1080 ms and not subsiding significantly during the protracted retention period. Moreover, the differential complexity of the novel words phonology significantly affected pupillary activation. Overall, these preliminary results point to the effectiveness of pupillometry as a technique for capturing the cognitive effort entailed in the short-term maintenance of novel word forms in the phonological loop, a process deemed crucial in the everyday novel word learning process. Results are discussed in view of future research that could establish and extend their implications.

Background: Children with autism spectrum disorder (ASD) show certain characteristics in visual attention. These may generate differences with non-autistic children in the integration of relevant social information to set the basis of communication. Reliable and objective measurement of these characteristics in a language learning context could contribute to a more accurate early diagnosis of ASD. Gaze following and pupil dilation are being studied as possible reliable measures of visual attention for the early detection of ASD. The eye-tracking methodology allows objective measurement of these biomarkers. The aim of this study is to determine whether measurements of gaze following and pupillary dilation in a linguistic interaction task are potential objective biomarkers for the early diagnosis of ASD. Method: A group of 20 children between 17 and 24 months of age, made up of 10 neurotypical children (NT) and 10 children with an increased likelihood of developing ASD were paired together according to chronological age. A human face on a monitor pronounced pseudowords associated with pseudo-objects. Gaze following and pupil dilation were registered during the task These measurements were captured using eye-tracking methodology. Results: Significant statistical differences were found in the time of gaze fixation on the human face and on the object, as well as in the number of gazes. Children with an increased possibility of developing ASD showed a slightly higher pupil dilation than NT children. However, this difference was not statistically significant. Nevertheless, their pupil dilation was uniform throughout the different periods of the task while NT participants showed greater dilation on hearing the pseudoword. Conclusions: The fixing and the duration of gaze, objectively measured by a Tobii eye-tracking system, could be considered as potential biomarkers for early detection of ASD. Additionally, pupil dilation measurement could reflect differential activation patterns during word processing in possible ASD toddlers and NT toddlers.

The aim was to test the use of eye-tracking methodology for the early detection of ASD in a task of association between unfamiliar objects and pseudowords. Significant differences were found between ASD (n = 57) and TD (n = 57) Spanish speaking toddlers in the number and time of fixation. The TD children showed more and longer fixations on eyes and mouth while the ASD children attended almost exclusively to objects, making it difficult to integrate lexical and phonological information. Moreover, the TD toddlers looked at the mouth when the pseudoword was produced while the ASD toddlers did not. Gaze fixation on eyes and mouth during word learning recorded by eye-tracking may be used as a biomarker for the early diagnosis of ASD.

(1) Background: Children with autism spectrum disorder (ASD) show certain characteristics in visual attention which generate difficulties in the integration of relevant social information to set the basis of communication. Gaze following and pupil dilation could be used to identify signs for the early detection of ASD. Eye-tracking methodology allows objective measurement of these anomalies in visual attention. The aim is to determine whether measurements of gaze following and pupillary dilation in a linguistic interaction task, captured using eye-tracking methodology, are objective for early diagnosis of ASD. (2) Methods: 20 children between 17 and 24 months of age, made up of 10 neurotypical children and 10 children with ASD were paired together according to chronological age. A human face on a monitor pronounced pseudowords associated with pseudo-objects. Gaze following and pupil dilation was registered during the task. (3) Results: Significant statistical differences were found in the time of gaze fixation on the human face and on the object, as well as in the number of gazes. Also, there were significant differences in the maximum peak of pupil dilation, this being found in the neurotypical group at the moment of processing of the pseudoword, and in the ASD group in the baseline prior to the task (4) Conclusions: The registration and the duration of gaze, and the measurement of pupil dilation with ‘eye-tracker’ are objective measures for early detection of ASD.