Coagulopathy is known as one of the most challenging effects of COVID-19, and the effects of acute airway diseases resulting from the coronavirus on pregnant mothers and their fetuses can be dangerous. Two women who were pregnant suffering from coagulopathy (one of them with disseminated intravascular coagulation (DIC) and the other one with hypercoagulation) and COVID-19 infection are reported in this study. During hospitalization due to severe vaginal bleeding and placental detachment, cesarean section was performed on the first case and because of acute severe DIC, she received a massive transfusion. The second patient presented with epigastric pain and tachycardia and positive D-dimer, which was eventually treated with a diagnosis of bilateral lower extremities DVT. COVID-19 might have a variety of effects on pregnancy outcome, from vascular and placental involvement to respiratory involvement; there is an association between the coronavirus and hypercoagulopathy state and coagulopathy like DIC.
Background: endometrial cancer is the most frequent genital cancer in women in the developing nation. The purpose of this study was to investigate on the demographic and clinical aspects of endometrial cancer, or to explain its epidemiology in patients admitted to Urmia's Kosar Hospital.
Methods: From 2006 to 2016, the medical records of 179 hospitalized women with an initial diagnosis of endometrial cancer were analyzed in this cross-sectional research. The patients’ clinical and demographic information, including age, menstrual age, first visit reason, number of deliveries, menstrual pattern, history of previous disease in patients and their relatives, disease stage, clinical parameters (including WBC, Hb, and MCV), pathology type, and the presence or absence of metastasis was extracted from their medical records and analyzed.
Results: The patients in our research had a mean age of more than 50 years. Nearly 80% of the patients were menopausal, and approximately 90% of the patients presented with bleeding complaints. Patients with endometrioid type adenocarcinoma had the highest frequency of pathology.
Conclusion: Our findings show a high proportion of bleeding complaints among the patients evaluated, which might reflect the importance of this finding and help to guide the disease’s diagnosis and therapy. However, further research is needed to establish the epidemiology of this condition in the country.
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