The Trivers-Willard hypothesis suggests that populations respond to scarcity by decreasing the ratio of males to females at livebirth. Cuba experienced an extreme economic depression in the 1990s called the "special period." Using time-series analysis, the authors studied the impact of this event on the male:female sex ratio at birth in Cuba from 1960 to 2008. From 1990 to 1993, the per capita gross domestic product in Cuba decreased by 36%. By use of a definition of the special period from 1991 to 1998, there was a prolonged increase in the male:female ratio of livebirths during this period of economic depression (P < 0.001), from 1.06 at baseline to a peak of 1.18. This association persisted when using alternative definitions of the duration of economic depression in sensitivity analyses. Once the period of economic depression was over, the male:female ratio returned to the baseline value. These data suggest that, in Cuba, contrary to the Trivers-Willard hypothesis, the human population responded to conditions of scarcity by increasing the ratio of males to females at livebirth. These data may be relevant in the modeling of demographic projections in countries that experience prolonged economic depression and in understanding adaptive human reproductive responses to environmental change.

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The aim of this study is to analyse the performance evolution of all, and the dominant, team’s performances throughout an eight-season period within the Spanish professional basketball league. Match-related statistics were gathered from all regular season matches (n = 2426) played during the period 2009–2010 to 2016–2017. The non-metric multidimensional scaling model was used to examine the team’s profiles across seasons and for the most successful (playoff) teams. The main results showed that: 3-point field goals made (effect size, d = 0.61; 90% confidence interval, CI = 0.23; 1.37) and missed (d = 0.72; 90% CI = 0.35; 1.46), and assists (d = 1.27; 90% CI = 0.82; 1.86) presented a positive trend with an increased number of actions across the seasons; 2-point field goals made (d = 0.21; 90% CI = −1.25; 2.02) and missed (d = 0.27; 90% CI = −0.52; 0.92) were decreased; free throws made and missed, rebounds, fouls, blocks, steals and turnovers showed a relatively stable performance. The matrix solution (stress = 0.22, rmse (root mean squared error) = 7.9 × 104, maximum residual = 5.8 × 103) indicated minimal season-to-season evolution with the ordination plot and convex hulls overlapping. The two most dominant teams exhibited unique match patterns with the most successful team’s pattern, a potential benchmark for others who exhibited more dynamic evolutions (and less success). The current findings identified the different performances of teams within the Spanish professional basketball league over eight seasons with further statistical modelling of match play performances useful to identify temporal trends and support coaches with training and competition preparations.

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Cuba at these ages) to December 2018. Method: Retrospective descriptive study of the total number of adolescents diagnosed with HIV in Cuba in the period January 1987 to December 2018. La information was obtained from the record of sexually transmitted infections (STIs) and HIV/AIDS of the National Epidemiology Directorate of the Ministry of Public Health (MINSAP). Results: The universe was made up of the2090cases diagnosed with male predominance for a63.3with low percentages in the ages of 10 to 14 years with 38 cases (1.8%) throughout the epidemic, 1,434 (68.6) remain in asymptomatic status and 656 cases have developed AIDS for 31.4%. Of those who died of AIDS alone on the 14th. 5% of the 303 cases have died from this cause. As for its location, the highest percentages are in Outpatient Care. Conclusions: Predominance of the male sex, the source of transmission was fundamentally homosexual. The highest percentage of those diagnosed with HIV is in outpatient status. lion in 2015 and 7.7 million in 2010. Intensified efforts to expand treatment coverage, mainly for children and adolescents, which in 2016 were included in ART programs, are still needed. The World Health Organization (WHO) supports countries to accelerate their efforts to diagnose and treat these vulnerable population groups in a timely way [1]. The African region remains also the hardest hit, with nearly two-thirds of the world's new HIV infections [1].

Table of contentsA1 Characterization of the immunoallergic profile towards the proteins of the wheat flour in Cuban populationRaúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Beatriz Tamargo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria, Alexis Labrada, Maytee MateoA2 Are peanuts causing food allergy in Cuba?Maytee Mateo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria, Mary Carmen Reyes Zamora, Beatriz Tamargo, Alexis LabradaA3 Prick test and immunoallergic profile to soy allergens in Cuban populationOmar Herrera, Maytee Mateo, Raysa Cruz, Mirta Alvarez Castello, Alexander Ciria, Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Alexis LabradaA4 Skin sensitization and immunoallergic profile to hen's egg in Cuban populationJosé Severino Rodríguez Canosa, Raysa Cruz, Maytee Mateo, Mirta Alvarez Castello, Alexander Ciria, Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Alexis LabradaA5 Sensitization to three domestic mites in patients with adverse food events to shellfishMirta Alvarez Castello, Raúl Lázaro Castro Almarales, Alexis Labrada, BiocenA6 Diagnostic efficacy by skin prick test with allergenic extracts of legumes in Cuban patientsYamilet Ibizate Novales, Ilonka Estruch Fajardo, Alexis Labrada, Maytee Mateo, Armando GinardA7 Baked egg goods without wheat flour carry an increased risk of reactionBruce Lanser, Anna Faino, Erwin Gelfand, Pia HaukA8 Prevalence, incidence and associated risk factors of adverse reaction to food in Cuban infants - a population-based prospective studySilvia Venero Fernández, Julia Urbina, Mirta Alvarez Castello, Raúl Lázaro Castro Almarales, Ramón Suárez Medina, Hermes Fundora Hernández, John Britton, Andrew William FogartyA9 Microbiome in ice machines and assessing the plasma nanotechnology in breaking the biofilm and improving air qualityNabarun Ghosh, Clinton Ross Bell, Chandini Revanna, Constantine Saadeh, Jeff Bennert, Danius Bouyi, Mitsy Veloz, Nelofar SheraliA10 Characteristics of patients with food allergy in health public serviceMagna CoelhoA11 Allergic rhinitis and asthma index increased in Texas panhandle and AHPCO and plasma nanotechnology as solutionsNabarun Ghosh, Jeff Bennert, Danius Bouyi, Constantine Saadeh, Clinton Ross Bell, Mitsy Veloz, Chandini Revanna, Nelofar SheraliA12 Antigen-specific T follicular helper cells mediate peanut allergy in miceJoseph J. Dolence, Takao Kobayashi, Koji Iijima, Hirohito Kita, Hirohito Kita, Ashli Moore, James KrempskiA13 Production of recombinant Mal d 3, a major apple allergen, in Pichia Pastoris, to investigate the impact of the food matrix and post-translational modifications on Mal d 3 immuno-reactivityRoberta Aina, Riccardo Asero, Sabine Pfeifer, Pawel Dubiela, Merima Bublin, Christian Radauer, Piotr Humeniuk, Karin Hoffmann-SommergruberA14 Reaction to sports drink: no whey! Whey allergy in absence of clinical cow’s milk allergyFrank Eidelman, Ves Dimov, Charl KhalilA15 Food allergy on Tumblr: focus on teena...

Introduction: Chagas disease (CD) is a common cause of advanced heart failure in Colombia and the third cause of heart transplant in our center. For transplanted patients the immunomodulatory therapy is crucial, but it makes them susceptible to CD reactivation. Fiorelli et al showed a frequency of reactivation of 40% based in histological diagnosis; also, Gray et al reported a frequency of 61% using quantitative PCR. The estimation of this phenomenon in our population is essential to improve its management. Methods: We performed a retrospective cohort study of patients with heart transplant due to chagasic cardiomyopathy. The primary outcome was the prevalence of CD reactivation. Secondary outcomes included the description of clinical manifestations, immunomodulatory therapies used and the time elapsed since the transplant until the reactivation. Reactivation was defined as a positive RT-PCR for T.cruzi after heart transplant or a compatible endomyocardial biopsy. The RT-PCR test was performed if clinical deterioration, ventricular disfunction, or either randomly according to physician criteria. Results: Fifteen patients were included in the analysis. The age at the moment of the transplant was 54 YO (IQR 43-56), 67% were men. CD reactivation was diagnosed in the 67% of patients (Figure 1a). The median of the time to CD reactivation after the transplant is 12 months (95%-CI:3,16-20,8) (Figure 1b). The mortality during follow-up was 0% and the longest follow-up time was 11 years.The most frequently used drugs in patients with reactivation were cyclosporine, tacrolimus and corticosteroids. All of the patients with reactivation received benznidazole. Conclusions: There is a high prevalence of CD reactivation in heart transplanted patients due to Chagasic cardiomyopathy, especially during the first year. Protocols for screening these condition are necessary for an adequate care of these patients. Cualitative RT-PCR test and myocardial biopsy should be considered.