Cardiovascular diseases are the most significant factors leading to death. This quasi-experimental study was carried out on 28 non athletic men. Subjects were divided into 4 groups. To the first group water (400 cc) was given, the second group received whey protein supplementation (50g), the third group had cheese juice (50g), and milk was given to the fourth one (400 cc), immediately after the training session. High -density lipoprotein (HDL), its sub fractions HDL2 and HDL3 cholesterol, apolipoprotein M, gastric inhibitory polypeptide and estradiol were evaluated prior to and after training for 12 sessions, three sessions in each week. The differences were not significant for gastric inhibitory polypeptide (GIP) and estradiol in the fourth group after training in comparison with the first phase. A significant decrease in apolipoprotein M-HDL total cholesterol on resting level were observed in all four groups and in HDL3 cholesterol with cheese juice and also whey protein in comparison with prior phase (P-values were 0.02, 0.001, 0.000, 0.015, respectively) (0.01, 0.01). A significant increase in HDL2 cholesterol level was observed in the groups with cheese juice and whey protein in comparison with their prior phases (P-values were 0.02, 0.03, respectively). This study showed that circuit resistance training has positive effects on the lipid profile changes in untrained young men.
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