The solubilities of mercury(II) octadecanoate (MOD) In water, formamide, Af.Af-dhnethylformamlde, and cyclohexanone have been determined at 5 K Intervals over the temperature range 293-328 K by using mercury-203 as a tracer. In water, Af.Af-dlmethylformamlde, and cyclohexanone, the solubility of MOD Increases with Increase of temperature whereas In formamide It shows a slight decrease. The entropies of solution at 298.15 K calculated from solubility results are Indicative of strong solute-solvent Interactions resulting In either complexatlon or Intermolecular bonding of MOD with the polar solvents.
INTRODUCTION: The usefulness of drains on seroma formation after surgery for breast cancer is the most
investigated and most controversial topic of debate for the clinical researchers. Hence this study was conducted to
compare single drain and double drain among women with breast cancer who underwent MRM in preventing seroma formation and also to
determine the role of other predictors on the same. MATERIAL AND METHODS: A hospital based non-randomized controlled trial was
conducted among 84 women (42 women each in single drain and double drain group respectively) with breast cancer who underwent modied
radical mastectomy in the department of General Surgery, GSVM Medical College, Kanpur from January 2019 to October 2020. All women
were followed up after insertion of either single or double drain following MRM for seroma formation. The mean age of the study RESULTS:
participants was 46.4 (12.1) years. The incidence of seroma formation was found to be 26.2% (95% CI: 17.5%-37.1%). On logistic regression
2
analysis there was a signicant association for BMI > 25 kg/m , hypertension and lymph node status with seroma formation. However, there was
no signicant association for age, Diabetes Mellitus and number of drains (p>0.05) in logistic regression analysis. CONCLUSION AND
RECOMMENDATIONS: Single or double drain techniques are equally effective in reducing the seroma formation ad associated
complications following modied radical mastectomy. Lymph node status, BMI and hypertension were found to inuence seroma formation in
our study. Further research with a larger sample size at a multicentric level is needed to make our study results robust for better management of
these patients.
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