OBJECTIVE: To find the incidence of systemic causes of menorrhagia with special emphasis on careful history taking, clinical examination and inclusion of simple blood tests to diagnose hemostatic disorders. METHOD: Thirty two women with menorrhagia of 15-45 years age, without any pelvic cause and treated from 1st January, 2011 to 31st December, 2011 were recruited for this study. After a detailed history and general examination all patients were subjected to blood tests for complete blood count, bleeding time, prothrombin time, activated partial thromboplastin time (aPTT) and serum T3, T4, TSH levels. Special tests were reserved, wherever applicable, to diagnose the cause of menorrhagia. Results were analyzed statistically by 2 x 2 chi square test. RESULTS: Hypothyroidism (25%) and inherited coagulopathy (18%) were the two most common nonpelvic causes of menorrhagia. Menorrhagia from menarche (P<0.001), bleeding from other sites (P=0.007), history of previous operative bleeding (P<0.001), and history of postpartum bleeding (P<0.001) were statistically significant in patients with underlying hemostatic disorders.
CONCLUSION(S):A detailed history, clinical examination and simple blood tests can detect systemic causes of menorrhagia.
BACKGROUND AND OBJECTIVESDysfunctional uterine bleeding is an abnormal bleeding from the uterus in absence of organic disease of genital tract and demonstrable extragenital cause. Thyroid dysfunction is marked by large number of menstrual aberrations. This study aimed at detecting thyroid dysfunction and further evaluating in patients with a provisional diagnosis of DUB.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.