Background: The management of PPROM remains controversial. Aim of this study was to determine the fetomaternal outcome in conservative management of PPROM.Methods: A prospective observational study was done on a total of 110 pregnant women between 24 and 36 weeks 6 days gestation with PPROM visiting Geetanjali medical college and hospital from February 2019 to July 2020. All the patients were subjected to detailed history and examination and followed till their delivery.Results: The incidence of PPROM in our study was 4.94%. The mean latency period from membrane rupture to delivery decreased from 12.1±14 days at >28 weeks, 5.3±7.7 days at 28-31 weeks 6 days to 1.1±1.2 days at 32 to 36 weeks 6 days. The most common indication of LSCS was fetal distress (26.31%). E. coli was the most common organism (36.36%) isolated and it was significantly associated with gestational age at PPROM (p value <0.040405). The maternal morbidity was 24.53% and was closely associated with the gestational age at PPROM (p value <0.001). The perinatal morbidity was 44.20% and perinatal mortality was 13.04% which was mainly due to RDS (33.34%).Conclusions: Management of PPROM involves complete evaluation of risks and benefits of conservative management. The treatment should be directed toward conserving the pregnancy with prophylactic use of antibiotics and corticosteroids thereby reducing fetomaternal morbidity and mortality. However, termination of pregnancy should be considered at the earliest suspicion of chorioamnionitis, septicaemia.
Background: Anovulatory infertility is present in 75% of patients with polycystic ovarian syndrome (PCOS), in addition to oligomenorrhoea and signs and symptoms of hyperandrogenism. This study was performed to evaluate the role of laparoscopic ovarian drilling (LOD) on ovulation, restoring menstrual cycles and pregnancy in clomiphene resistant women with PCOS.Methods: This prospective cohort study included 50 women who were diagnosed with PCOS and anovulatory infertility. These patients had already tried Clomiphene citrate for conception and did not ovulate, underwent LOD between 1st September 2009 until February 2011 in the Department of Gynecology and Obstetrics, at the Panna Dhay Mahila Chikitasalya, Udaipur. The major outcome measures include spontaneous ovulation, menstrual regularity after LOD and pregnancy rates.Results: Among 50 patients 33 (66%) started to menstruate regularly and 60% ovulated spontaneously, of them 24 (48%) conceived.Conclusions: Women with PCOS respond favourably to LOD.
Background: To determine the effects of vaginal bleeding occurring in first and second trimester on maternal and fetal outcome.Methods: The present prospective observational study was conducted at department of obstetrics and gynecology, Geetanjali medical college and hospital, Udaipur and 90 Patients with first and second trimester pregnancy (till 24 weeks of gestation) presented with the complaint of vaginal bleeding at antenatal clinic or emergency were included in this study.Results: In our study the result showed that bleeding in early pregnancy is associated with high rate of abortion (32.22%) in which first trimester abortion constitute 44.83% while second trimester abortion constitute around 55.17%. Outcome observed in women having bleeding with SCH 58.4% had caesarean delivery followed by 25% had vaginal delivery, 16.7% had preeclampsia, 8.3% had PPROM and 5.6% had APH. Similarly, in women having bleeding without SCH 64% had caesarean delivery followed by 36% had vaginal delivery, 12% had preeclampsia, PPROM and APH in 8% each and also women having bleeding with SCH, 37.1% had low birth babies, 22.8% had NICU admission and 8.6% had birth asphyxia. Similarly, in women having bleeding without SCH, 16% had low birth babies, 16% had NICU admission and 8% had birth asphyxia.Conclusions: First and second trimester vaginal bleeding is an independent risk factor for an adverse obstetric outcome and this risk factor should be taken into consideration when deciding upon antenatal surveillance and management.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.