Water extract of pomegranate ash (WEPA), an agro waste (bio) derived novel and sustainable medium, has been developed for the Ullmann coupling of aryl halides under added base, ligand and reducing agent free palladium catalysis in open-air.
Ac onvenient and efficient palladium(II)-porphyrin catalytic system has been developed for the Suzuki-Miyaura cross-coupling (SMC) of aryl bromides with potassium aryltrifluoroborate in water.Aseries of seven different porphyrins and their complexes with palladium (Pd II (por)-1-Pd II (por)-7) were prepared, and screenedt heir catalytic activity in making biaryls through C(sp 2 )ÀC(sp 2 )c oupling.S ignificantly, the present protocol utilizes safe, water-soluble, and highly stable porphyrins as an alternative to toxic and unstable phosphine ligands. Thes imple preparation of porphyrins and their complexes, use of moisture-resistantc atalyst, excellent yields of the isolated products,u se of eco-friendly solvent( such as water), and reusability of the catalysta re the notable advantages of this method. This finding uses marginally explored, moisture-insensitive potassium phenyltrifluoroborates as nucleophilesf or SMC. Furthermore, the scope of the methodh as been demonstrated for the multigram scale preparation of biaryls without any side products.Supporting information and the ORCID identification number(s) for the author(s) of this article can be found under http://dx.
A facile palladium(II)‐porphyrin catalytic system has been developed for the Mizoroki‐Heck coupling of aryl bromides with alkyl acrylates under mild conditions. Seven different porphyrins (H2TPP, H2TpCPP, H2TpAP, H2TpTP, H2TSTpSPP, H2TmHPP and H2TmCPP) and their complexes with palladium (Pd‐TPP, Pd‐TpCPP, Pd‐TpAP, Pd‐TpTP, Pd‐TSTpSPP, Pd‐TmHPP and Pd‐TmCPP) were synthesized, and examined their catalytic role in the synthesis of alkyl cinnamates in DMF. The complex, Pd‐TSTpSPP showed better activity in the present conversion. This finding has significant advantages like operational simplicity, easy synthesis of porphyrin ligands and their complexes with palladium, utilization of safer and recyclable catalyst and high yields of Mizoroki‐Heck products.
The imines of Ellman's tert-butylsulfinamides have become one of the elementary substrates for the construction of chiral precursors and complex organic molecules. This article reports a mechanochemical access to imines of chiral tert-butylsulfinamides with a variety of aldehydes using solid acid catalyst, perchloric acid-silica (HClO 4 ⋅SiO 2 ) at innocuous reaction environs. The conversion can be carried out at ambient temperature under solvent and metal-free conditions by (hand) grinding the contents in a mortar at open-air. The current protocol is highly economical, allows large-scale preparation, offers a very good to nearly quantitative yields of imines in short reaction times with no product racemization and doesn't necessitate the moisture-free conditions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.