Background and Objective: Severe head injury has an incidence of about 10% of total head injuries, severe head injury has the highest mortality rate. In head injury patients, Mean arterial pressure (MAP) value can affect the patient's mortality rate related to brain perfusion. This research aims to know mortality of severe head injury patients based on the mean arterial pressure at Ulin Hospital Banjarmasin in January 2018 – October 2021 period. Subject and Method: This research was retrospective descriptive study, with collected data from medical records using purposive sampling technique. Result: The results showed from 51 people diagnosed with severe head injury, death 72.5% and alive 27.5%. Mortality rate 100% with MAP < 50 mmHg, 77% with MAP > 150 mmHg. And in MAP 50-150 mmHg mortality rate about 62%. Measurement of MAP in patient with severe head injury affect the mortality rate related to brain perfusion which depends on intracranial pressure (ICP) and MAP. Mean arterial pressure affect cerebral blood flow. Adequate brain perfusion are factors to decrease mortality and increase survival outcome. Conclusion: mean arterial pressure affect mortality rate in patient with severe head injury
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