Probiotics are the health promoting viable microorganisms that exhibit a beneficial effect on the health of human being by improving the intestinal microbial balance. Probiotic bacteria may produce various compounds, which are inhibitory to the growth of pathogen, which include organic acids (lactic and acetic acids), bacteriocins, and reuterin. In the present study a total of 17 food samples were collected for isolation of lactic acid bacteria. A total of 26 isolates of lactic acid bacteria were purified and screened for their antimicrobial activity against seven human pathogenic MTCC strains counting three test fungal strains such as Aspergillus fumigatus, Aspergillus sp. and Candida albicans and four test bacterial strains (two Gram-negative namely Escherichia coli, Salmonella enterica ser. typhi and two Gram-positive Staphylococcus epidermidis and Bacillus amyloliquifaciens). Out of 26, eight isolates were considered for further analysis of probiotic potential whose antimicrobial activity was found to be good against maximum number of tested strains. The selected lactic acid bacteria exhibited excellent probiotic characteristics and thus can be used as a potential source of probiotic. Study affirms their use in the development of new pharmaceutical preparations and functional foods belonging to vegetables and fruits (as origin) as probiotics for the betterment of public health.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.