Contudol capsule, a combination of four herbal extracts namely Boswellia serrata, Curcuma longa, Moringa oleifera and Zingiber officinale was chosen for the study. Two lots of Contudol capsule were analyzed qualitatively and quantitatively by applying various classical and instrumental methods. Along with general test parameters of capsules like average weight, filled average weight, uniformity of weight, disintegration time, blends of both the capsule lots were tested for loss on drying, total ash content, acid insoluble ash, extractive values, pH by appropriate standardized classical and instrumental methods. Active components like Boswellic acid content was found to be around 129.15 and 131.33 mg per capsule by titration method in respective lots, whereas, spectrophotometric analysis for Curcumin and titrimetric analysis of Tannin content showed 20.806 mg, 20.005 mg and 2.063 mg, 1.883 mg per capsule respectively in corresponding lots. Presence of gingerol was well illustrated by modern sophisticated HPTLC technique, where, in Diethyl ether : Hexane (7:3) system, after spraying with VSR, resembling blue colored spots were observed at Rf about 0.20, 0.40 and 0.70 in reference standard, extract powder and blend of the capsule. Heavy metals like Arsenic, Mercury, Lead and Cadmium were found to be at the ppm level within the limits set by AYUSH, by Inductively Coupled Plasma spectrometry. Microbiological testing was carried out as per the USP/ BP guidelines and findings were complying with the pharmacopoeial specified values. In this way, by considering these entire test parameters one can very well establish and maintain the quality of polyherbal formulations.