Phaeohyphomycoses are rare fungal infections, caused by dematiaceous fungi, manifested as cutaneous and subcutaneous infections, meningitis, sinusitis, keratitis, osteomyelitis and disseminated infection. This is a case report of a 45year old immuno compromised female on ART (Anti Retroviral therapy) presented with fever and generalized nodular lesions draining pus on face, hands, axilla, groin and labia majora since one month. Biopsy of the subcutaneous nodule on the lateral aspect of the thigh revealed septate fungal hyphae on 10% KOH (10% Potassium Hydroxide) mount. Fungal culture of the biopsy material on SDA (Sabouraud's Dextrose Agar) at 25 0 C showed cotton wooly, dark gray to olivaceous black growth with black reverse and identified as dematiaceous fungi belonging to Exserohilum species by microscopy. The patient was put on Itraconazole 200mg BD in combination with Terbinafine 250mg BD for which she responded with healing of pustular lesions in two weeks and complete remission in two months.
Spleen is a solid reticuloendothelial organ attached to stomach and kidney with ligaments.Pathologically spleen is majorly associated with haematological disorders. The commonly encountered splenic lesions are as a result of either parasitic infections or trauma. Other causes are rare and often a neglected entity. Splenic lesions can be unifocal or multifocal. The splenic lesions can be categorized as -Congenital, normal variants, infective (acute, chronic), traumatic and mass lesions (benign or malignant). Infective and malignant lesions can be either primary originating in spleen or secondary. Metastatic focal lesions of spleen are frequently seen in malignant melanoma, renal cell carcinoma, breast carcinoma and ovarian neoplasms. Aim of our article is to review imaging findings and highlight the patterns and presentations of different splenic lesions and broaden the horizon of diagnosis from haematological pathologies to a wide varieties of existing pathologies in spleen which are often undiagnosed, missed or overlooked.
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