BACKGROUND Intermediate Uveitis also known as pars planitis essentially affects the pars plana of ciliary body and periphery of choroid. It occurs particularly in young adults with female predominance. Determining the aetiology of intermediate uveitis is one of the most difficult problem in curing the patient. This is a study of presentation, progression and follow up of a group of people diagnosed as intermediate uveitis, seeking medical care in south Indian population. MATERIALS AND METHODS A prospective study was done to identify the pattern of uveitis in a uveitis clinic population of a major referral centre in South India. A total number of 25 patient and 30 eyes were followed from January 2016 to April 2017. A standard clinical protocol, laboratory investigations, were used for the final diagnosis. A standard treatment protocol was followed and patients were reviewed accordingly. RESULTS There were 13 female and 12 male patients. Mean age of presentation was 29 ± 3.6 years (with a range of 10-47 years). Among the 25 patient 15 were bilateral rest being unilateral. Among the cases 3 presented with grade 1 vitritis, 15 with grade 2 vitritis, 5 with grade 3 vitritis and 2 with grade 4 vitritis. Snowballs were seen in inferior quadrant of 7 patients. Among the 25 cases, 10 had ocular tuberculosis, 6 had sarcoidosis, 2 had multiple sclerosis and 7 diagnosed to be pars planitis. All cases were given specific treatment according to their aetiology. In idiopathic cases periocular injection of triamcinolone was instituted. CONCLUSION Intermediate uveitis is a potentially vision threatening condition because of its chronic course and complications if appropriate therapy is not instituted. Thorough investigations to find out the underlying aetiology should be performed to institute cause specific treatment.
BACKGROUND Intermediate uveitis is a form of uveitis localised to the vitreous and peripheral retina. Primary sites of inflammation include the vitreous of which other such entities as pars planitis, posterior cyclitis and hyalitis are encompassed. The aim of this study was to describe the demographic features and clinical outcomes in patients with intermediate uveitis. MATERIALS AND METHODS 39 patients were included in our study for the institution of antituberculous therapy. After obtaining informed consent, they underwent a complete ophthalmological examination. All patients of presumed tuberculous aetiology underwent Mantoux skin testing, ESR, chest x-ray and QuantiFERON gold TB testing when necessary. All patients were started on antituberculous therapy along with oral prednisolone. Reduction in vitritis by two grades or improvement in BCVA by two lines was considered as response to therapy along with reduction in recurrence of inflammation. Patients were reviewed periodically. RESULTS The mean age of the study population was 35.4 years. The patients presented with symptoms like defective vision and the commonest sign was vitritis. The commonest complication encountered in our study was cystoid macular oedema. The recurrences were found to be lower when compared to the episodes before the institution of antituberculous therapy and was found to be statistically significant (p<0.05). CONCLUSION In patients with intermediate uveitis, detailed evaluation should be carried out to rule out tuberculous aetiology. Prompt institution of antituberculous therapy may reduce complications and improve the visual outcome.
BACKGROUND Dry eye disease is one of the most common presentation in hospital with varied presenting complaints and which can lead to various complications. Study is done on 200 eyes diagnosed with dry eyes in a tertiary centre in South India using Schirmer; and tear break up time test. Their central corneal thickness is measured using specular microscopy. The correlation of dry eye disease and central corneal thickness is assessed. Dry eye disease diagnosed using Schirmer test showed a strong correlation with the central corneal thickness. A significant reduction in central corneal thickness was observed in dry eyes disease diagnosed with Schirmer disease. The factors affecting dryness includes inflammatory component and evaporating component. Based on my study the results of dry eyes due to inflammation of eye can be considered to have more association to the pathogenesis in relation to central corneal thickness. Inflammation decreases the eyes’ ability to produce normal tear. METHODS 200 eyes of 100 patients who presented in hospitals diagnosed with dry eye disease were included in the study. The central corneal thickness of these patients was measured and corelated with the degree of dryness using Shermer’s test and tear film break up time. RESULTS A statistical significance was observed between the inflammatory component causing dry eyes and the CCT values. CONCLUSIONS There is a significant association between the central corneal thickness and dry eye diseases. KEY WORDS Central Corneal Thickness, Schirmer’s Test, TBUT.
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