No abstract

Objective:The study was aimed to assess the incidence and characteristics of drug-related problems (DRPs).Methods:A prospective, observational study was conducted among 133 patients with stroke disease who were aged 18 years or older and admitted to the general medicine ward. During the 6 months study period, the incidence of DRPs was identified using the Pharmaceutical Care Network Europe Foundation classification system, version 6.2.Findings:A total of 133 patients were screened for DRPs. Among them, 120 patients have at least one DRP. A total of 254 DRPs were identified (on average, 2.015 DRPs per each patient case).Conclusion:Increasing the evidence of the incidence of medication-related problems in tertiary care hospitals indicates the need for the establishment of a clinical pharmacist in hospital settings.

Background: The use of "triggers" to identify Adverse Drug reactions (ADRs) is a novel emerging method for measuring the overall level of harm from medications in a health care organization. Our main objective is to determine the incidence of adverse drug reactions in the hospitalized patients and to compare Global Trigger Tool (GTT) with conventional method to identify ADRs. Methodology: A Prospective observational study was conducted over a period of six months during November 2016-April 2017. Modified Global Trigger Tool was used to identify triggers. 16 triggers were used to identify ADRs. Causality assessment ofADRs was done using Naranjo scale and severity and harm categorization of ADRs were assessed using NCC MERP. Results: A total of 244 patient profiles were analyzed. The results reveal that 193 triggers were identified in 125 patients and 93 ADRs were found in 81 patients. Out of which, 64(68.81%) ADRs were found by triggers and 29(31.18%) ADRs were found spontaneously without the presence of a trigger. There is a remarkable improvement in the identification of ADRs using trigger tool in comparison to traditional approach. Of 93 ADRs identified, 69 (74.19%) were probable and 24 (25.81%) were possible. Similarly, 65 (69.89%) were determined to be NCC-MERP harm category E and 28 (30.11%) were category F. Conclusion: The study results suggest that IHI global trigger tool could be useful to identify ADRs in hospitals twice as more efficiently when compared to traditional ADR identification methods. It is an effective method to enable clinical pharmacists to identify ADRs and management of the same.

Background: The use of "triggers" to identify Adverse Drug reactions (ADRs) is a novel emerging method for measuring the overall level of harm from medications in a health care organization. Our main objective is to determine the incidence of adverse drug reactions in the hospitalized patients and to compare Global Trigger Tool (GTT) with conventional method to identify ADRs. Methodology: A Prospective observational study was conducted over a period of six months during November 2016-April 2017. Modified Global Trigger Tool was used to identify triggers. 16 triggers were used to identify ADRs. Causality assessment of ADRs was done using Naranjo scale and severity and harm categorization of ADRs were assessed using NCC MERP. Results: A total of 244 patient profiles were analyzed. The results reveal that 193 triggers were identified in 125 patients and 93 ADRs were found in 81 patients. Out of which, 64 (68.81%) ADRs were found by triggers and 29(31.18%) ADRs were found spontaneously without the presence of a trigger. There is a remarkable improvement in the identification of ADRs using trigger tool in comparison to traditional approach. Of 93 ADRs identified, 69 (74.19%) were probable and 24 (25.81%) were possible. Similarly, 65 (69.89%) were determined to be NCC-MERP harm category E and 28 (30.11%) were category F. Conclusion: The study results suggest that IHI global trigger tool could be useful to identify ADRs in hospitals twice as more efficiently when compared to traditional ADR identification methods.It is an effective method to enable clinical pharmacists to identify ADRs and management of the same.