Background:The prevalence of adolescent obesity (15-18 years) in Indonesia continues to increase. The results of basic health research in 2013 showed the prevalence of adolescent obesity from 1.4% in 2010 increase to 7.3% in 2013. The condition of obesity will affect leptin secretion which plays a role in influencing food intake by controlling appetite in the hypothalamus and brain stem. Objective: This study aims to determine the description, differences, and correlations of the fat mass, visceral fat, and serum leptin levels in the group of adolescents who are overweight and obese. Design: This study was conducted by analytic survey method with cross sectional approachment. The sample consisted of 60 people aged above 18 years state as students of the Faculty of Medicine and Health Sciences Jambi University who were overweight and obese. Analyze data from the examination of fat mass, visceral fat, and serum leptin using the Pearson Correlation test and for the characteristics of FKIK Unja students aged above 18 years with BMI ≥23 will be analyze distributively. Results: The analysis showed significant results p = 0.000 and a high correlation of r = 0.719 between fat mass with leptin levels where the fat mass is directly proportional to leptin levels. The analysis showed that the results were not significant with p = 0.338 and did not correlate r = -0.126 between visceral fat and leptin levels. Conclusions: From this study obtained a body composition profile, leptin level profile and food intake data in overweight and obese adolescents, which will be used as initial screening to make lifestyle modifications and healthy behavior in overweight and obese adolescents so that in the future they will not be a risk factor for metabolic syndrome KEY WORDS: Obesity; Overweight; Fat mass; Visceral fat; Leptin ABSTRAK Latar belakang: Prevalensi obesitas remaja di Indonesia terus meningkat. Hal ini dapat berdampak buruk terhadap kesehatan karena obesitas berkaitan dengan noncommunicable diseases (penyakit-penyakit tidak menular). Keadaan obesitas yang ditandai dengan meningkatnya massa lemak dan lemak viseral akan mempengaruhi sekresi leptin dan menyebabkan terjadi resistensi leptin, dimana kondisi hiperleptinemia pada obesitas menjadi faktor risiko independen terhadap penyakit kardiovaskuler. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi masa lemak dan lemak viseral dengan kadar leptin pada remaja yang mengalami overweight dan obesitas Metode: Penelitian ini dilakukan dengan metode survey analitik dengan pendekatan cross sectional. Sampel berjumlah 60 orang remaja overweight dan obesitas dengan usia 17- 25 Analisa data hasil pemeriksaan massa lemak, lemak viseral, dan leptin serum menggunakan uji Korelasi Pearson dan untuk karakteristik mahasiswa FKIK Unja usia >18 tahun dengan IMT ≥23 akan dianalisis distributifnya. Hasil: Analisis menunjukkan hasil yang signifikan p = 0.000 serta korelasi r = 0,719 yang tinggi antara massa lemak dengan kadar leptin dimana massa lemak berbanding lurus dengan kadar leptin. Analisis menunjukkan hasil yang tidak signifikan dengan p = 0.338 serta tidak berkorelasi r = -0,126 antara lemak viseral dengan kadar leptin. kesimpulan: Dari penelitian ini didapatkan profil komposisi tubuh, profil kadar leptin dan data asupan makanan pada remaja yang overweight dan obesitas, yang akan dijadikan skrining awal untuk melakukan modifikasi gaya hidup dan perilaku hidup sehat pada remaja overweight dan obesitas sehingga kedepan tidak menjadi faktor risiko terkena sindroma metabolik. KATA KUNCI: Obesitas; Overweight; Masa lemak; Lemak viseral; Leptin
Background: Current nutritional status issues are no longer focused on malnutrition, but also on excess nutrition that can occur in all age groups, especially vulnerable to occur at a young age. Objective: to assess the effect of intensive clinical nutrition therapy on weight loss, body composition and lipid profile in overweight and obese adolescents. Method: This study was a case control study and was carried out during the months of August - September 2018, where the sample of the study would be antopometric examination, body composition and lipid profile before and after the intervention. Results: there was no significant difference in the effect of intervention between intensive nutrition therapy compared to only nutrition counseling in weight loss, body composition, and lipid profile. Conclusion: Nutritional intervention in the form of intensive nutrition therapy and counseling conducted in this study had significant results in weight loss, lipid profile and body composition in overweight and obese adolescents, although no significant effect was found on the two interventions. Keywords: Nutritional intervention, weight loss, body compotition, lipid profile, overweight, obesitas ABSTRAK Latar belakang: Permasalahan status gizi saat ini bukan lagi hanya terpusat pada kekurangan gizi saja, namun juga pada kelebihan gizi yang dapat terjadi pada semua golongan usia, terutama rentan terjadi pada usia muda. Tujuan: menilai pengaruh terapi gizi klinik intensif terhadap penurunan berat badan, komposisi tubuh dan profil lipid pada remaja overweight dan obesitas. Metode: Penelitian ini merupakan penelitian case control dan dilakukan selama bulan Agustus – September 2018, dimana sampel penelitian akan dilakukan pemeriksaan antopometri, komposisi tubuh dan profil lipid sebelum dan sesudah intervensi. Hasil: tidak terdapat perbedaan pengaruh intervensi secara bermakna antara terapi gizi intensif dibandingkan dengan hanya penyuluhan gizi saja dalam menurunkan berat badan, komposisi tubuh, dan profil lipid. Kesimpulan : intervensi gizi berupa terapi gizi intensif dan penyuluhan yang dilakukan pada penelitian ini memiliki hasil yang bermakna terhadap penurunan berat badan, profil lipid dan komposisi tubuh pada remaja overweight dan obesitas walaupun tidak ditemukan perbedaan yang bermakna dari kedua intervensi tersebut. Kata Kunci: intervensi gizi, penurunan berat badan, komposisi tubuh, profil lipid, overweight, obesitas
ABSTRACT Objective: the aim of the study is to investigate the correlation between vitamin D intake and serum 25(OH)D concentration of adult woman SLE patients. Methods: A cross-sectional study was conducted in 36 adult woman patients with SLE from Rheumatology Clinic of the Departemen of Internal Medicine Dr. Cipto Mangunkusumo hospital. Data collection included age, SLE classification, drugs, skin type, use of sunscreen, part of the body covered by clothes, length of sun exposure, body mass index (BMI), vitamin D intake, and serum 25(OH)D concentration. Results: Most of the subjects (41.7%) aged 36–45 years old, classified as mild SLE (52.8%), always used sunscreen (63.9%), skin type IV (69.4%), wearing clothes that covered all or almost of the body (69.4%), and not exposed or had sun exposure less than 30 minute (77.8%). All subjects used corticosteroid. Based on BMI half of the subjects had normal body weight, Based on AKG 2012 most (55.6%) had adequate vitamin D intakes, and 28 subjects (77.8%) were in vitamin D-deficient (serum 25(OH)D concentration <50 nmol/L). There were moderate positive correlation between vitamin D intake and serum 25(OH)D concentration in subjects (r = 0.52; P <0.01). Conclusion: There were moderate positive correlation between vitamin D intake and serum 25(OH)D concentration of adult woman SLE patients (r = 0.52; P <0.01). Key Words: Vitamin D; SLE; vitamin D intake; serum 25(OH)D concentration. ABSTRAK Tujuan: Tujuan penelitian ini adalah mengetahui korelasi antara asupan vitamin D dengan kadar 25(OH)Dserum pada pasien lupus eritematosus sistemik perempuan usia dewasa. Metode: Penelitian ini merupakan penelitian potong lintang pada 36 pasien SLE perempuan dewasa dari Poliklinik Reumatologi di RS Dr. Cipto Mangunkusumo. Pengambilan data subyek meliputi usia, klasifikasi penyakit SLE, obat-obatan yang digunakan, tipe kulit, penggunaan tabir surya, bagian tubuh yang tertutup pakaian, lama terpajan sinar matahari, indeks massa tubuh (IMT), asupan vitamin D, dan kadar 25(OH)D serum. Hasil: Sebagian besar (41,7%) subyek berusia antara 36–45 tahun, tergolong klasifikasi SLE ringan (52,8%), selalu menggunakan tabir surya (63,9%), tipe kulit IV (69,4%), dan memakai pakaian yang menutupi seluruh/sebagian besar tubuh (69,4%), serta tidak terpajan dan terpajan sinar matahari <30 menit (77,8%). Semua subyek menggunakan kortikosteroid. Separuh subyek memiliki berat badan normal berdasarkan IMT, sebagian besar (55,6%) subyek mempunyai asupan vitamin D cukup berdasarkan AKG 2012, dan 28 subyek (77,8%) menderita defisiensi vitamin D ( kadar 25(OH)D serum <50 nmol/L). Didapatkan korelasi positif yang sedang antara asupan vitamin D dengan kadar 25(OH)D serum pada subyek penelitian (r = 0,52; P <0,01). Kesimpulan: Terdapat korelasi positif yang sedang antara asupan vitamin D dengan kadar 25(OH)D serum pada pasien SLE perempuan dewasa (r = 0,52; P <0,01). Kata Kunci: Vitamin D; SLE; asupan vitamin D; kadar 25(OH)D serum.
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