BACKGROUNDOpioid dependence is a major public health problem in Kerala. Presence of psychiatric disorder among opioid dependent patients worsens the scenario. To date no attempts have been made to analyse the magnitude and pattern of comorbid psychiatric disorders in the state.
BACKGROUNDAdolescence is a period when individuals become independent from their parents. The period of adolescence itself is recognized as a period of 'stress and storm'. Stressful life events of both major and minor magnitude in the lives of adolescents are significantly related to their emotional behavioural problems. Studies on prevalence and pattern of stressors in adolescents using semi structured interview techniques and sound methodology is limited in developing countries. Knowing the magnitude of problem will help us in policy making.
Darier's disease is a rare autosomal dominant genodermatosis. There is a specific mutation in the ATP2A2 gene on chromosome 12q. Several neuropsychiatric manifestations have been described in association with Darier's disease. Most reports have come from western populations, with limited reports of Darier's disease and its neuropsychiatric associations among Asian people, although the demographic and clinical profiles are comparable. We present a case of 38 year old female from Kerala with Darier's disease presenting with schizophrenia spectrum disorder. Her first degree relatives have schizophrenia-like psychosis and dermatological manifestations suggestive of Darier's disease.
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