Curettage is one of the most common operations among women. Several methods are used to reduce post-operation pain. The present research seeks to study the effect of adding morphine and tramadol to lidocaine in para cervical block on post-operation analgesia. This is a double-blind clinical trial conducted on 120 women applying for curettage. The participants were divided into three completely random groups. The fi rst group received 5cc lidocaine 1.5% along with 1 mg (1cc) morphine (totally 6cc), the second group received lidocaine 1.5% and 2 mg (1cc) tramadol, and the third group received 5cc lidocaine with 1cc distilled water as placebo for para cervical block. The length and intensity of pain was registered based upon VAS table and time for requesting painkiller after operation for all three groups. The pain score in the 0th, 30th, and 60th minute in those groups receiving morphine and tramadol was less than what was observed in the group who had received lidocaine (P < 0.05), but the pain score in all times in the group who had received tramadol was signifi cantly less than other groups (P<0.05). The fi rst painkiller in morphine and tramadol groups was asked much later than lidocaine group (P < 0.05) but no signifi cant difference was observed between the morphine and tramadol groups. The side effects were similar in all groups with lower levels of Bradycardia observed in placebo group (P < 0.05). Morphine and tramadol were more effective than lidocaine creating para cervical block and analgesia and reduction of pain following the operation but tramadol exhibited a lower pain score throughout the research. The average length of analgesia in placebo group was less than what was observed in other two groups. However, no signifi cant difference was observed between tramadol and morphine groups in terms of the length of analgesia after operation.
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