Se-Phenyl selenocarboxylates have been conveniently prepared from (phenylseleno)acetylenes by treatment with ptoluenesulfonic acid monohydrate in dichloromethane. This easy conversion is compatible with a broad range of oxygenand nitrogen-containing functional groups. The Se-phenyl
A simple and stereospecific synthesis of both (R)-and (S)-GABOB has been developed. The synthetic approach involves the conversion, through organoselenium intermediates, of commercially available ethyl (R)-and (S)-4-chloro-3-hydroxybutyrate into a protected 1,2-amino alcohol with retention of the original configuration.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.