Cognitive enhancing drugs are claimed to improve cognitive functions such as learning and attention. However, little is known presently about the characteristics of off-prescription cognitive enhancing drug users or their perceived everyday experience with these drugs. As modafinil is the most commonly used off-prescription cognitive enhancing drug, the current study aimed to provide a detailed profile of modafinil users and their experiences and perceptions of this drug. To this end, an online survey, targeting cognitive enhancing drug users and students, was advertised on forum sites. Information was obtained regarding demographic data, illicit drug use, psychiatric diagnosis and experience of modafinil. Of the 404 respondents, 219 reported taking modafinil. Of these the majority were male, American or British, university-educated and currently employed, with a mean age of 27. Overall, modafinil was perceived by users as being safe. Modafinil users reported higher levels of illicit drug use and psychiatric diagnosis than would be expected from population-based data. More frequent reported modafinil use was associated with higher numbers of perceived benefits whilst reported frequency of use was not associated with the number of perceived risks. There was also a tentative link between the reported use of modafinil and the reported presence of psychiatric disorders, largely depression and anxiety. Respondents who had reported a psychiatric diagnosis declared higher subjective benefits of modafinil. This may suggest further beneficial effects of modafinil or it may reflect insufficient medical treatment for psychiatric disorders in some people. Overall, the findings of the current study should be beneficial in informing clinicians and legislative bodies about the modafinil user profile and how modafinil is perceived.

Few studies have examined the impact of alcohol on metacognition for witnessed events. We used a 2 × 2 balanced placebo design, where mock witnesses expected and drank alcohol, did not expect but drank alcohol, did not expect nor drank alcohol, or expected but did not drink alcohol. Participants watched a mock crime in a bar-lab, followed by free recall and a cued-recall test with or without the option to reply "don't know" (DK). Intoxicated mock witnesses' free recall was less complete but not less accurate. During cued-recall, alcohol led to lower accuracy, and reverse placebo participants gave more erroneous and fewer correct responses. Permitting and clarifying DK responses was associated with fewer errors and more correct responses for sober individuals; and intoxicated witnesses were less likely to opt out of erroneous responding to unanswerable questions. Our findings highlight the practical and theoretical importance of examining pharmacological effects of alcohol and expectancies in real-life settings.

This study was interested in investigating the existence of a shared psychological mechanism for the processing of expectations across domains. The literature on music and language shows that violations of expectations produce similar neural responses and violating the expectation in one domain may influence the processing of stimuli in the other domain. Like music and language, our social world is governed by a system of inherent rules or norms, such as fairness. The study therefore aimed to draw a parallel to the social domain and investigate whether a manipulation of melodic expectation can influence the processing of higher-level expectations of fairness. Specifically, we aimed to investigate whether the presence of an unexpected melody enhances or reduces participants' sensitivity to the violations of fairness and the behavioural reactions associated with these. We embedded a manipulation of melodic expectation within a social decision-making paradigm, whereby musically expected and unexpected stimuli will be simultaneously presented with fair and unfair divisions in a third-party altruistic punishment game. Behavioural and electroencephalographic responses were recorded. Results from the pre-planned analyses show that participants are less likely to punish when melodies are more unexpected and that violations of fairness norms elicit medial frontal negativity (MFN)-life effects. Because no significant interactions between melodic expectancy and fairness of the division were found, results fail to provide evidence of a shared mechanism for the processing of expectations. Exploratory analyses show two additional effects: (i) unfair divisions elicit an early attentional component (P2), probably associated with stimulus saliency, and (ii) mid-value divisions elicit a late MFN-like component, probably reflecting stimulus ambiguity. Future studies could build on these results to further investigate the effect of the cross-domain influence of music on the processing of social stimuli on these early and late components.