Opiate overdose is a significant cause of mortality among injection drug users (IDUs) in the United States (US). Opiate overdose can be reversed by administering naloxone, an opiate antagonist. Among IDUs, prevalence of witnessing overdose events is high, and the provision of take-home naloxone to IDUs can be an important intervention to reduce the number of overdose fatalities. The Drug Overdose Prevention and Education (DOPE) Project was the first naloxone prescription program (NPP) established in partnership with a county health department (San Francisco Department of Public Health), and is one of the longest running NPPs in the USA. From September 2003 to December 2009, 1,942 individuals were trained and prescribed naloxone through the DOPE Project, of whom 24% returned to receive a naloxone refill, and 11% reported using naloxone during an overdose event. Of 399 overdose events where naloxone was used, participants reported that 89% were reversed. In addition, 83% of participants who reported overdose reversal attributed the reversal to their administration of naloxone, and fewer than 1% reported serious adverse effects. Findings from the DOPE Project add to a growing body of research that suggests that IDUs at high risk of witnessing overdose events are willing to be trained on overdose response strategies and use take-home naloxone during overdose events to prevent deaths.

No abstract

No abstract

The Social Supply Chain and the Future High Street http://researchonline.ljmu.ac.uk/id/eprint/1950/ Article LJMU has developed LJMU Research Online for users to access the research output of the University more effectively. The Social Supply Chain and the Future High StreetAbstract Purpose: The paper examines how independent social and commercial activities have developed in response to the perceived decline in the UK High Street and in response to the challenges of increasing digital retailing opportunities. This examination is undertaken through the lens of the social supply chain as a means to understanding, suggesting and expanding on current research regarding retailing and the UK High Street. We reveal some of the challenges being posed by the changing patterns of growth and consumption in cities and couple these with shifting supply chain trends.Design : A case study approach is employed to explore the rapid advances and influence of digital technologies on businesses operating on the primary business street of suburban centre, towns or cities (described in the UK collectively as the 'high street'). The study is conducted through the analytical lens of the social supply chain.Originality : For the purpose of this paper we use two distinct strategies relating to delivery and balancing and in relation to the actions of cocreation, coproduction and coconsumption to emphasise and analyse changes currently occurring in the UK high street. We take a social supply chain management perspective to undertake a systematic critical review of the various recent efforts undertaken by local governments, communities and traders groups to revitalise the high street.Findings : Theoretically extending the 'social' in the social supply chain we illustrate the usefulness of the nuanced concept of the 'social supply chain' with two related strategies concerning delivery and balance. These strategies are themselves interlinked with the actions of cocreation, coproduction and coconsumption. Examples of social supply chain strategies presented include retail businesses giving away something as an incentive, where the underlying requirement from the customer is that they will bring their own specialist product, skill or social network to a specified location (real or virtual).