Background: Rheumatic heart disease is a condition in which the heart valves have been permanently damaged by rheumatic fever and high-alert medications. medications that are most likely to cause significant harm to the pregnant women, even when used as intended. Aim: This study aimed to evaluate the effect of nursing educational guideline regarding high alert medication for pregnant women suffering from rheumatic heart diseases. Design: A quasi experimental design was used to achieve the aim of the current study one group. Setting: The current study was conducted in the outpatient clinics at obstetrics and Gynecology at Alshohadaa Central Hospital in Menoufia governorate, which belongs to the Ministry of Health and Population-Egypt. Sample: A convenience sample composed of 64 pregnant women among high-alert medication and rheumatic heart disease were included in the study. Tools: Tool 1: Self-Administered Questionnaire consisting of: Socio-demographic characteristics of pregnant women, Obstetrical history, menstrual history and pregnant women knowledge assessment sheet about rheumatic heart disease and high alert medication. Tool 2: Guideline sheet for pregnant women with rheumatic heart diseases & high alert medication. Results: There is statistically significant relation between total knowledge about rheumatic heart diseases and total knowledge about high-alert medications.
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