The aim of the present study is to through lights on the biochemical relations between H. pylori infection and the changes in serum Ammonia, Gastrin, Leptin, Amylase, Lipid profile, Iron, Total Iron Binding Capacity, Transferrin, Haptoglobin and Vitamin B12. 90-helicobacter pylori infected patients, and 20-clinically healthy subjects used as control all ages ranged between 25 to over 65 years are applied in the experiment. The result of the present study showed the association between serum Ammonia and Amylase, Gastrin and Leptin levels, in addition to serum lipid profile including (Total cholesterol, Triacylglycerol (TG), Low density lipoprotein-cholesterol (LDL-C) and High density lipoprotein-cholesterol (HDL-C), Iron status (Iron, Ferritin, Total Iron Binding capacity (TIBC) and Transferrin) in addition to Vitamin B12 and haptoglobin with helicobacter pylori infection. These parameters may all be regarded as predictors or risk factors for Gastritis, anemia, peptic ulcer, Gastric cancer and Coronary heart diseases in elderly patients. The findings of the present study suggest that, helicobacter pylori infection are primary interacting mediators in the anemia and different diseases of the stomach.
This study was performed to investigate the biochemical alteration of Biochemical effects of Helicobacter pylori infection on iron metabolism and its related components in human. Ninety Patients (male & female) were divided according to ages into four groups; the group (I) contained 20 healthy individuals aged (10-65) years used as control for all groups. Group (II): consisted from 30 infected patients with Helicobacter pylori aged (10-25) years. Group (III): consisted from 30 infected patients with Helicobacter pylori aged (25-40) years. Group (IV): consisted from 30 infected patients with Helicobacter pylori aged (40-65) years. The blood samples were collected and the obtained results revealed that, Significant increases in serum gastrin amylase, ammonia, total iron binding capacity (TIBC), transferrin, total cholesterol, triacylglycerols (Tg), low density lipoprotein-cholesterol (LDL), very low density lipoprotein-cholesterol (VLDL), high density lipoprotein-cholesterol (HDL) Furthermore, significant decreases were in plasma serum iron, Ferritin, haptoglobin, Vitamin B 12 , leptin and HDL in compared to control group. From the obtained results it could be concluded that, we must take car from Helicobacter pylori.
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