Objectives: The present study aimed to compare the presence of E. gingivalis in immunocompromised patients with periodontitis and conrol group by measuring immunological parameter (ECP) by using ELISA. Methadology: A Comparison case-control study design was done on 80 samples [40 case ( 20 immunocompromised patients with peridontitis + 20 immunocompromised patients without peridontitis) were selected from Al-Sader Medical City/Middle Euphrates Cancer Center and 40 control (Diabetes Mellitus patients with poor oral sanitation)] were selected from AL-Najaf Center for Diabetes and Endocrinology/Al-Sadr Medical City, during the period from the beginning of November 2021 to the end of February 2022. Age range of cases and control between (20 - ≥ 60) years. Results: The results of the Salivery Tests (Immunological Cytokines Assays) showed the concentration levels of ECP was (6.6860 ± 2.97386Pg/ml) in immunocompromised patients with Periodontitis. But in immunocompromised patients without Periodontitis was (4.7280 ± 3.46401 Pg/ml). While in control group (Diabetic Mellitus Poor Oral Sanitation) was (49.294 ± 22.42156 Pg/ml). Conclusion: The infection rate of the E.gingivalis parasite in the control group (Diabetic Mellitus Poor Oral Sanitation) was twice higher than that of the immunocompromised patients with peridontitis and without peridontitis.
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