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The extent of migration of plasticizer from haemodialysis lines into saline and plasma has been examined and a number of different types of tubing have been compared. A model system designed to simulate in vivo haemodialysis was evolved. The method uses a continuous cyclohexane extraction in order to mimic uptake of plasticizer by body tissues. Although not an ideal system, the results obtained are indicative of the extent to which the plasticizers are leached.

Styrene-acrylic copolymer surfactants demonstrate significant dispersant erformance advantages in suspension concentrate formulations versus current industry standards. The formulation requirement of dispersant to maintain the active ingredient in suspension upon dilution was significantly lower with styrene-acrylic dispersants Atlox® Metasperse 100L or Atlox® Metasperse 500L than with other commercially available anionic surfactants. When blended with Atlas® G5000 and Synperonic® A7 nonionic surfactants, low viscosity suspension concentrate formulations can be developed using either Atlox® Metasperse 100L or Atlox® Metasperse 500L. Equally important is the use of experimental design techniques to monitor how subtle changes in surfactant ratio can affect formulation performance and aid the formulation chemist in selecting the optimum performing surfactant system.

Choice and concentration of latex emulsion polymer is critical to the development of a seed coating which demonstrates excellent properties of abrasion resistance and seed flowability without adversely affecting seed germination and ultimate crop yield. With low use rate insecticides and fungicides as seed coatings it is important to form a continuous coating over the seed surface by optimum addition of polymer and/or solid diluent. Use of the experimental design associated with blending allows the formulator to identify this precise composition and provides a framework for comparing the performance of alternative emulsion polymers and diluent solids. Built-in seed coating formulations of low use rate insecticides and fungicides, developed by the addition of 5–20 %w/w emulsion polymer, demonstrate comparable abrasion resistance to the suspension concentrate itself.