An infusion of 180 mEq sodium acetate was given to nine dialysis patients and eight normal volunteers simulating the transfer of acetate that occurs during 30 min of rapid hemodialysis. While serum acetate concentrations had almost normalized 15 min after the end of infusion, there was no increase in serum cholesterol and triglyceride concentrations. In this short-term study, acetate does not appear to be a major contributing factor for the hyperlipidemia of dialysis patients.
use in the development of future therapies aimed at restoring the correct gene expression and thus phenotype in failing cardiomyocytes.
M45Diazoxide and ischaemic preconditioning act differently on the mitochondria: is the mitoKATP channel a red herring? KHH Lim, SA Javadov, SJ Clarke, M-S Suleiman, GD Angelini, AP Halestrap.Bristol Heart Institute, Bristol Royal Infirmary, Bristol UK.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.