Objective. In our study, we wanted to identify the number of existing deformities of the spine and posture in primary schoolers. Methods. The sample consisted of 311 healthy pupils aged 6-7. We used Klein, Thomas, and Mayer method to evaluate the posture. The spine curvature was evaluated by plumb line. Muscle imbalance was evaluated by standardized manual tests by Professor Janda. The results were evaluated by the basic population abundance and the use of the ANOVA program. We determined the level of statistical significance at p = 0.05. Results. The statistically significant occurrence of poor posture was found. Poor posture occurred in more than 50% of the pupils studied. Spine deformities in the sagittal plane have exceeded 30% (C = 37.94212%; Th = 32.15434%; L = 30.22508%). In the frontal plane deformities were present in 13.18328% of pupils. Spinae and postural disorders were accompanied by the muscle imbalance (muscle stiffness and weakness). Conclusion. Screening is a well-founded technique for the early detection of spinae and posture disorders. Based on the results of screening, professionals can take preventive measures. As in our research prevalence of spine deformities and poor posture in children was high, we recommend regular screening in clinical practice.
Conclusions: Thanks to cooperation with key stakeholders and payers and additional verification with MoH, we were able to establish important base for the indirect costs associated with depression. Indirect costsas additional state payer costsshould play important role in complex evaluations of existing and new technologies coming to the segment of the depression treatment.
Insurance Company (V seobecná zdravotná pois tovna, V sZP). We used the "bottomup" approach that helped us identify, quantify and value resources in a disaggregated way, so that each element of the cost was estimated individually and they were summed up at the end, similarly to our first research conducted previously. We calculated real direct costs for the model patient with MM from the diagnosis to death. Results: Based on internal cost resources provided upon request from V sZP, we identified real direct costs associated with MM from the diagnosis till death (% from total direct costs,
Objectives: There is limited understanding of the resource utilization associated with AML pre and post midostaurin approval. The study objectives were to evaluate healthcare resource utilization between FLT3-mutated AML patients and FLT3wildtype AML patients, pre-midostaurin approval and among FLT3-mutated AML patients post-midostaurin approval. Methods: Retrospective medical charts from the Huntsman Cancer Institute (HCI) identified AML patients treated with 7+3 induction chemotherapy from 2007 to July 2018. FLT3-mutated patients (FLT3m) were treated with chemotherapy and midostaurin (mido) from May 2017 to December 2018. Historical FLT3m patients and FLT3-wildtype (FLT3-wt) patients, prior to midostaurin approval, comprise FLT3m pre-mido and FLT3-wt groups, respectively. Health resource utilization including number of inpatient, outpatient, emergency visits and length of stay were determined. Results: FLT3m mido, FLT3m pre-mido and FLT3-wt groups included 7, 39 and 61 patients respectively. Overall AML-related median inpatient and outpatient visits for FLT3m mido was 9 and 50 respectively. Overall median inpatient and outpatient visits for FLT3m pre-mido and FLT3-wt were not significantly different with 5 and 6 visits (p=0.1); 47 and 51 visits (p=0.4), respectively. Compared to FLT3-wt patients, consolidation therapy for FLT3m premido patients was shorter (78 vs 33 days, p=0.0015) and consisted of fewer cycles (3 vs 2 cycles, p=0.0009) respectively. As a result, during consolidation therapy, FLT3m pre-mido patients had significantly fewer overall hospital visits (4 vs 14 visits, p=0.0006). There were no significant differences in utilization between FLT3m premido and FLT3-wt groups during other treatment settings. FLT3m pre-mido patients also underwent transplant earlier than FLT3-wt patients after diagnosis (125 vs 186 days, p=0.0028). Conclusions: FLT3m pre-mido patients had fewer consolidation cycles and underwent transplant earlier than FLT3-wt patients. Utilization was significantly lower for FLT3m-pre-mido patients compared to FLT3-wt patients during consolidation regimen despite similar overall utilization.
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