Azadirachta indica commonly known as Neem, is an evergreen tree. Since time immemorial it has been used by Indian people for treatment of various diseases due to its medicinal properties. It possesses anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, anti-oxidant, astringent, anti-viral, cytotoxic, and anti-inflammatory activity. Nimbidin, Azadirachtin and nimbinin are active compounds present in Neem which are responsible for antibacterial activity. Neem bark is used as an active ingredient in a number of toothpastes and toothpowders. Neem bark has anti-bacterial properties, it is quite useful in dentistry for curing gingival problems and maintaining oral health in a natural way. Neem twigs are used as oral deodorant, toothache reliever and for cleaning of teeth. The objective of this article is to focus on the various aspects of Azadirachta indica in dentistry in order to provide a tool for future research.

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Purpose:Miliaria is also known as Sweat rash or Prickly heat, common aliment of the eccrine sweat glands that often occurs in conditions of increased heat and humidity. It is especially prevalent in babies and infants. Miliaria crystalline is the one which cause multiple tiny blisters resulting in rapidly evolving noninflammatory vesicles. The present study was mainly carried out to explore the use of herbal plants primarily Neem (Azadirachta indica) and Mint (Mentha arvensis) leaves for the development of AntiMiliaria cotton fabrics using AATCC methods.Method:Methanolic extracts of the poly herb were prepared. Microorganisms were isolated, microbiologic and histological features of the samples were evaluated. The preliminary antimicrobial activity of different extracts was performed by agar well diffusion method. The phytochemical analysis of the extracts was evaluated using standard procedures. After evaluation, the crude poly herbal extracts were coated on to the cotton fabrics using pad dry cure method. The antimicrobial assessment of poly herb treated cotton fabrics assessed using AATCC standard methods.Result:The organisms isolated from the Miliaria samples are Staphylococcus epidermis. The preliminary results showed that Neem (Azadirachta indica) and mint (Mentha arvensis) leaves having better antimicrobial activity against Staphylococcus epidermis. The Poly herbal treated fabrics were further characterized chemically. The Antimicrobial assessment of poly herb treated cotton fabrics showed increased antimicrobial activity than control fabric. It showed 100% bacterial reduction in poly herb treated fabrics until 10 washes.Conclusion:The use of medicinal plants is a worldwide phenomenon. Every part of the world prefers medicinal herbs to treat disease than commercially available antibiotics. Further in vivo studies will help to understand the mechanism of action of antimicrobial fabrics on the Miliaria infection.

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