In this paper, Artificial Neural Networks (ANN) are used to model an extraction process that uses a supercritical fluid as solvent which its pilot installation is located at the Institute of Experimental and Technological Biology -IBET in Oeiras -LisbonPortugal. A strategy is used to complement the experimental data collected in laboratory during extraction procedures of useful compositions for the pharmaceutical industry using Black Agglomerate Residues (BAR) originating from of the cork production as raw material. The strategy involves fitting of data obtained during an operation of extraction. Two neural models are presented: the neural model trained using a Mean Square Error (MSE) minimization algorithm and the neural model which the learning was based on the error entropy minimization. A comparison of the performance of the two models is presented.
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