Background: In this study, we compared ophthalmic artery Doppler indices between normotensive and hypertensive pregnant women in third trimester and then evaluated if the alterations in ophthalmic artery doppler indices were seen in all the types of hypertensions in pregnancy or confined to preclaampsia. Further we tried to see correlation of ophthalmic artery Doppler indices with perinatal outcomes in terms of fetal growth restriction (FGR), prematurity, neonatal intensive care unit admission (NICU) and maternal outcomes and tried to arrive at mean values of ophthalmic artery Doppler indices to predict adverse outcomes.
Methods: 50 hypertensive and 50 normotensive pregnant women were recruited in third trimester. A thorough history about hypertension was taken, obstetric scan was done to know estimated fetal weight, and doppler of umbilical, middle cerebral artery, uterine arteries was done. Simultaneously maternal ophthalmic artery Doppler readings were taken, women were followed up after delivery and perinatal outcomes were recorded.
Results: Comparison of mean values of ophthalmic artery doppler parameters in women with and without hypertension showed statistically significant differences with respect to the peak systolic velocity 2 (PSV2), PI (pulsatility index), RI (resistivity index) and peak ratio (PR) (PR=PSV2/PSV1). Significant difference was found only in PR value in preeclampsia group compared to other subgroups of hypertension. In the hypertension group complicated with FGR the mean peak ratio=0.8 whereas in the hypertension group requiring preterm delivery the mean peak ratio=0.78, and in the hypertension group requiring NICU admission the mean peak ratio=0.81. At ophthalmic artery PR cut off ≤0.725, the sensitivity and specificity were 76% and 65% respectively to predict FGR.
Conclusions: Pregnancy complicated by hypertension showed alterations in ophthalmic artery Doppler indices. Among the subgroups of hypertension, ophthalmic artery PR was the best index for discriminating preclampsia from other types and it was significantly higher in hypertensive pregnant women who had adverse perinatal outcomes. Ophthalmic artery PR has almost similar performance as uterine artery PI in indicating FGR in our study. It could also indicate maternal disease severity such as hypertensive crisis requiring ICU admission, the study number was small.
Poster abstractswere rated to enable highly diagnostic confidence (82.9%), and produce better image quality for the near field image (94.3%), the far field image (88.6%), and overall (94.3%). Conclusions: The current study described an objective method of comparing image quality acquired using different sonographic technologies. Ultrasound transducer incorporated with PureWave Crystal technology produces significantly better image quality for diagnostic purpose. Department of Fetal Medicine, Herlev Hospital, Herlev, Denmark; 18 Department of Fetal Medicine, Glostrup Hospital, Glostrup, Denmark; 19 Department of Obstetrics and Gynecology, Gentofte Hospital, Gentofte, Denmark; 20 Department of Obstetrics and Gynecology, Hilleroed Hospital, Hilleroed, Denmark; 21 Deaprtment of Fetal Medicine, Hvidovre Hospital, Hvidovre, Denmark Background: In 2004 the Danish Board of Health issued a new guideline on prenatal diagnosis and screening. Pregnant women are offered a first trimester combined risk assessment for T21 and a second trimester anomaly scan. Denmark has a public hospital system where 21 departments perform screening in pregnancy, all using the same software system, Astraia, to store screening data. The yearly number of deliveries is 65,000 and the uptake of screening is higher than 92%. The Database IT solution has been developed in close cooperation with Astraia gmbh,
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Objective: Preeclampsia is most commoniy encountered problem in pregnancy. The aim of the present study was to assess the levels of beta HCG in preeclampsia and normal women without hypertension. Method: This was a prospective case control study undertaken on 25 preeclamptic patients and 25 healthy antenatal women in OB-GYN Department of Rajah Muthiah Medical College, Annamalai University between the periods of 2016-2018.
Result:The mean maternal serum β-human chorionic gonadotropin levels in preeclampsia were 44463.26±30595.25miu/ml that is significantly greater than normotensives (7346.200±4479.0855 of p value< 0.001). The number of complications in the preeclampsia group are increased than the normal antenatal women group. Conclusion: Mean βhcg levels tend to be significantly more in preeclampsia than healthy pregnant mothers. The higher β hcg levels associated with more neonatal and maternal complications.
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