BACKGROUNDBreast cancer is the second leading cause of cancer deaths in women today. Important risk factors for female breast cancer include age (increases as women gets older), genetics, early onset of menarche and late age of menopause, family or personal history of breast cancer, obesity, nulliparity, use of HRT and OCPs, consumption of alcohol and a middle to high socioeconomic status. Diffusionweighted imaging is a new MR imaging technique in which contrast within the image is based on microscopic motion of water. It is reported to be highly sensitive for evaluation of breast cancer and a possible means of differentiating benign and malignant tumour. Diffusion is quantified by measuring apparent diffusion coefficient (ADC). This study was performed to determine whether diffusionweighted imaging can be useful for diagnosis of mammographically detected BIRADS 3 & 4 lesions, correlating with histopathological diagnosis and to derive ADC values which may allow distinguishing benign from malignant lesions.
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