Male rats and pregnant and nonpregnant female rats of the Wistar strain were sham-exposed or exposed to static (0.49 T) or to extremely low frequency (50 Hz) magnetic fields (0.018 T) 2 h per day for 20 consecutive days. Measures of irritability, exploratory activity, and locomotion were made in that order before and after the 4th, 10th, and 17th 2-h exposures. A reliable decrease in the irritability of rats after repeated exposure to a static or undulating field was found. No significant effects of treatment conditions on open-field behavior and locomotor activity were observed. Pregnancy had no influence on the behavioral end points. These results indicate that irritability of rats may be used as a simple behavioral indicant of mammalian sensitivity to magnetic fields.
Effects of Electromagnetic Field on Free‐ Radical Processes in Steelworkers. Part I: Magnetic Field Influence on the Antioxidant Activity in Red Blood Cells and Plasma: Bogusfaw Kula, et al. Department of Experimental and Clinical Biochemistry, Silesian School of Medicine, Poland—The purpose of the study was the evaluation of electromagnetic field (electric field strength of 20 V/ m, f=50 Hz and magnetic field strength of 2 A/m, f=50 Hz) effects on the antioxydative activity in steelworkers’ red blood cells and plasma. The plasma GSH‐Px (EC 1.11.1.9) activity, MDA and ceruloplasmin levels as well as SOD (EC 1.15.1.1.), CAT (EC 1.11.1.6) and GSH‐ Px (EC 1.11.1.9) in red blood cells were measured. Statistically significant decreases in red blood cells SOD and GSH‐Px activities, a CAT activity increase and plasma MDA increase and a ceruloplasmin decrease were found in workers exposed for 3‐10 yr and for longer than 10 yr to electromagnetic fields. No statistically significant changes in the parameters evaluated were found among steelworkers employed for shorter than 3 yr. All changes observed among workers exposed to electromagnetic fields result in adaptative responses by activating systems controlling the balance of body oxidative mechanisms.
Cultured fibroblasts isolated from murine livers by tissue trypsinization were exposed to a static magnetic field (0.490 T) and to extremely low frequency (ELF) magnetic field (50 Hz, 0.020 T). The cultures were exposed to magnetic fields on four consecutive days for exposure times of 2, 4, 8, 16, 32, and 64 min. After such exposures and obtaining of fibroblast subcellular fractions, lipid peroxidation product-malondialdehyde (MDA) was measured. Increased peroxidation of fibroblasts' membrane structures exposed to an ELF magnetic field was observed in subcellular fractions-microsomal, mitochondrial, and nuclear. No changes in peroxidation of membrane structures were found in fibroblasts exposed to a static magnetic field.
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