Methemoglobinemia is an altered state of haemoglobin that leads to impaired oxygen delivery to the body tissues. Deliberate ingestion of certain herbicides may lead to this condition. Modern herbicides are often synthetic mimics of natural plant hormones that interfere with growth of the target plants. These modern herbicides act by various mechanisms some of them being Acetyl co-enzyme A carboxylase inhibition, aceto lactate synthase inhibition, photosystem II inhibition, 4-hydroxy phenyl pyruvate dioxygenase inhibition and so on. We report a case of Methemoglobinemia after deliberate ingestion of an herbicide marketed to be safe and containing only biological extracts and filters. The patient was treated with ascorbic acid successfully. Our paper emphasizes the use of ascorbic acid as an alternative method in the treatment of Methemoglobinemia. Ascorbic acid is the main stay of treatment in patients with G6PD deficiency.
OBJECTIVES:The purpose of this study was to evaluate the accuracy and reliability of Mobile Application-Based Software for chair side cephalometric analysis. MATERIALS AND METHOD:Pretreatment lateral cephalograms of 20 patients (10 males and 10 females) were selected randomly and were traced manually and also using Application-based software (One Ceph). 20 angular and three linear parameters were measured both manually and with the software in all the patients. Inter and intra-operator reliability of one ceph was evaluated and the measured parameters were statistically compared with the manual method (Gold Standard). RESULT:The accuracy of angular and linear values was compared for all 23 parameters and our results showed no significant difference in the two methods used for most of the measurements. Three of the measurements [Angle of convexity (N-A; A-Pog); ANB angle; Upper Incisor to NA (Angular)] did show a statistically significant difference though these were clinically irrelevant. CONCLUSION:Application-based cephalometric analysis can be an effective clinical diagnostic tool for chair-side cephalometric evaluation of orthodontic patient.
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