Absorption of lactulose and mannitol was measured in eleven patients with atopic eczema and lactulose/mannitol excretion ratios were calculated. Mean lactulose absorption was increased in the patients with exzema and their excretion ratios were higher than those of controls. There was no correlation between either eczema extent or severity and the excretion ratio. We conclude that small intestinal passive permeability is increased in some patients with atopic eczema.
SUMMARY
Staining of the nails due to hydroquinone‐containing creams is not a well‐recognized condition. We report two cases in older women in whom brown discoloration developed after the use of cosmetic skin‐lightening creams for actinic lentigines of the hands. The cause of the discoloration and its relation to light exposure is discussed.
Complications due to ear piercing are well recognized and include local infection, septicaemia, hepatits, tuberculosis, traumatic laceration, embedded studs, bleeding, nickel dermatitis, gold dermatitis, large scars, keloids, epidermal cysts, cleft ear lobe syndrome, post‐auricular pressure sores and frostbite due to ethyl chloride spray. We wish to report a sarcoidal tissue reaction after ear piercing which does not appear to have been previously reported.
Cutaneous sensation in plaques of necrobiosis lipoidica was assessed in five non-diabetic and seven diabetic patients. Eleven of the twelve showed partial or complete anaesthesia of the affected skin. These findings are important in the differential diagnosis of tuberculoid leprosy. Further studies of nerve function in cutaneous granulomas need to be carried out.
Summary
A single blind comparison of 0·1% dithranol in a 17% urea cream base (Psoradrate®) with a coal tar and salicyclic acid pomade in the treatment of scalp psoriasis is described. Roth treatments were equally effective, though Psoradrate caused significantly more side‐effects. We concluded that Psoradrate is effective in the treatment of scalp psoriasis.
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