Simultaneous utilization of methanol and glucose by Hansenvla polymorpha (Toru1opsi.s sp.)M H 26 results in a n increase in growth yield of up to 18% in dependence of the mixing proportion.The distribution of carbon from 14C-methanol into biomass and carbon dioxide was investigated. The distribution pattern was strongly influenced by the mixing proportion showing that methanol plays an increasing role as an energy donor as the glucose content in the mixture increased. Due to these data and verified by theoretical considerations the effect on growth yield was discussed to be caused by a n interconnection in the conversion of the individual substrates. This is attributed to glucose delivering the acceptor for C,-assimilation and resulting in n more efficient utilization of glucose carbon on the one as well as the energy content of methanol on the other hand.
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