Manganese has been proven to be an essential trace element in animals since 1931. Today, it is known that manganese deficiency results in a wide variety of structural and physiological defects in animals. For humans, the safe and adequate range of intakes for manganese by enteral nutrition is 2.0 to 5 mg per day; for parenteral nutrition a range of 0.15 to 0.8 mg per day is proposed. The manganese content of components of enteral nutrition (EN) and total parenteral nutrition (TPN) solutions is determined using electrothermal atomic absorption spectrometry. Comparison is made between calculated and measured values. The manganese present in supplementary nutrition and flavor stuffs is also measured. The intake of manganese by EN is calculated based on the daily administration, and is found to vary from 192 to 7373 micrograms per day. In prepared TPN-solutions, the manganese contribution of all components before adding the Oligo Complex is found to be less than 0.2% of the total manganese content. After addition of the Oligo Complex mixture, a mean daily intake of 5.02 +/- 0.16 mg per day is found.
The influence of instrumental parameters on the determination of Mn using EAAS is investigated and the interference of several acids, cations and anions determined. When NaCl or KCI is present an interference sup ressor, such as L-ascorbic acid, has to be added. The contamination resulting from dust particles in the kborato or from a mixer is found to be negligible. Using NBS sam les several destruction techniques are investigged and comparison is made with results obtained by FAA$?
INTRODUCTIONAlthough manganese has been known for a long time to be a constituent of animal tissues, it was first shown to be an essential trace element for animals in 1931 when Kemmerer and coworkers (1) and Orent and McCollum (2) demonstrated poor growth in mice and abnormal reproduction in rat fed diet without manganese.Manganese is widely distributed and its concentration is in most cases not extremely low. However, precise biochemical roles for manganese are not clear. Therefore, an accurate and sensitive method for the determination of this element in foods, diets and body fluids is necessary.Electrothermal atomic absorption spectrometry (EMS) remains perhaps one of the most used techniques in biomedical research. Low detection limits can be obtained, but important matrix interferences can be significant for this method (3).The purpose of this study is to evaluate the instrumental and the matrix interferences on the determination of manganese by EAAS in foods and biochemical samples and to compare these results with literature values.
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