Objectives:To identify coronary plaque morphology using grey scale and virtual histology intravascular ultrasound in patients with and without elevated glycated haemoglobin.Methods: The cross-sectional study was conducted at the Cardiology Department of Kafrelsheikh University, Egypt, from November 2019 to January 2022, and comprised adult patients of either gender suffering from acute coronary syndrome admitted for catheterisation. The patients were divided into three groups.Diabetic patients were in group A, prediabetic patients with elevated glycated haemoglobin in group B, and patients with normal glycated haemoglobin in group C. All patients were subjected to clinical examination, 12-lead electrocardiogram, coronary angiography and multimodality intravascular ultrasonography scan of proximal segments 3-6cmof non-culprit coronary arteries intra group differences were compared using the analysis of variance (ANOVA) test.Continue..
Objective: To evaluate plaque morphology in non-culprit coronary arteries using intravascular ultrasound in patients with acute coronary syndrome with and without elevated glycated haemoglobin and its assocaition with patient outcome.Methods: The cross-sectional study was conducted at the Cardiology Department of Kafrelsheikh University, Egypt, from November 2019 to January 2022, and comprised adult patients of either gender suffering from acute coronary syndrome. The patients were divided into three groups. Diabetic patients were in group A, prediabetic patients with elevated glycated haemoglobin in group B, and patients with normal glycated haemoglobin in group C. The patients were subjected to coronary angiography and percutaneous coronary intervention. Intravascular ultrasound scan wasdone after succcessful intervention. Lesions were classified according to ultrasound findings. Patients were followed up for one year to observe subsequent events to the morphology of the lesions detected at baseline. Data was analysed using SPSS 20.Results: Of the 52 patients, 18(34.7%) were females and 34(65.3%) were males. Group A had 18(34.6%)patients; 13(72%) males and 5(28%) females with mean age 57.9±6.9 years. Group B had 17(32.7%) patients; 11(64.7%) males and 6(35.3%) females with mean age 56.5±5.5 years. Group C had 17(32.7%) patients; 10(59%) males and 7(41%) females with mean age 59.5±5.1 years (p>0.05). Thin-capped fibro-atheroma was significantly higher in groups A and B compared to group C (p=0.045). Significant direct correlation between major adverse cardiac events and prevalence of thin-capped fibro-atheroma was found between groups A and C (p=0.033), and between groups B and C (p=0.047)regarding prevalence of necrotic plaque and subsequent myocardial infarction.Conclusion: Thin-capped fibro-atheroma was the more common plaque type in patients with raised glycated haemoglobin, and the subsequent rate of major adverse cardiac events was significantly higher in such patients compared to the non-diabetic population.Keywords: Plaque, Atherosclerotic, Angiography, Vessels, Percutaneous, Prediabetic.
Background: In the United States, stroke is the third leading cause of mortality and one of the leading causes of permanent disability. Previous studies have revealed that cardioembolic strokes account for 15-30% of ischemic strokes, making cardiac assessment critical in these individuals.Low ejection fraction (EF) and severe valvular disease are the most prevalent causes of cardiac embolism. When it comes to determining the cause of cardiac embolism, TEE is the best imaging technique. For the majority of patients, invasive LA function measures aren't an option. TEE data in patients with primary valvular heart disease were used to examine the relationship between the LA functional parameter and the LAA function. Methods: In the cardiology department, a cross-sectional single-center research was conducted. Patients with known valvular heart disease were included in the study. We found that the mean age of the participants in our research was 44.1613.59, and there was no statistically significant difference in the prevalence of hypertension, diabetes, or smoking. It has been shown that the LAA velocity and the LA maximum system strain (r= 0.615; P 0.001), strain rate (r= 0.623) are strongly linked. TDI-derived peak sys strain correlated well with LAA velocity, as did the peak strain rate.
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