Metachronal waves commonly exist in natural cilia carpets. These emergent phenomena, which originate from phase differences between neighbouring self-beating cilia, are essential for biological transport processes including locomotion, liquid pumping, feeding, and cell delivery. However, studies of such complex active systems are limited, particularly from the experimental side. Here we report magnetically actuated, soft, artificial cilia carpets. By stretching and folding onto curved templates, programmable magnetization patterns can be encoded into artificial cilia carpets, which exhibit metachronal waves in dynamic magnetic fields. We have tested both the transport capabilities in a fluid environment and the locomotion capabilities on a solid surface. This robotic system provides a highly customizable experimental platform that not only assists in understanding fundamental rules of natural cilia carpets, but also paves a path to cilia-inspired soft robots for future biomedical applications.
One of the challenges of minimally invasive surgery is the dexterous manipulation and precise control of small‐diameter continuum surgical instruments. Herein, a magnetic continuum device with variable stiffness (VS) is presented, whose tip is precisely shaped and controlled using an external magnetic field. Based on a low melting point alloy (LMPA), the serial segments composing the continuum device are independently softened via electrical current and remotely deformed under a magnetic torque, whereas the rest of the device is locked in place. The resulting system has the advantage of combining the precision of magnetic navigation with additional degrees of freedom provided by changing the segments stiffness. With a minimum diameter as small as 2.33 mm and an inner working channel, the magnetic continuum device with VS is adapted to use in several therapeutic scenarios, including radio‐frequency cardiac ablations and interventional endoscopy in the gastrointestinal tract. The magnetic torque is used to remotely control the shape of the soft sections, whereas the stiff sections remain unchanged, thus adding degrees of freedom to the magnetic continuum device.
Minimally invasive robotic surgery often requires functional tools that can change their compliance to adapt to the environment and surgical needs. This paper proposes a submillimeter continuous variable stiffness catheter equipped with a phase-change alloy that has a high stiffness variation in its different states, allowing for rapid compliance control. Variable stiffness is achieved through a variable phase boundary in the alloy due to a controlled radial temperature gradient. This catheter can be safely navigated in its soft state and rigidified to the required stiffness during operation to apply a desired force at the tip. The maximal contact force that the catheter applies to tissue can be continuously modified by a factor of 400 (≈20 mN-8 N). The catheter is equipped with a magnet and a micro-gripper to perform a fully robotic ophthalmic minimally invasive surgery on an eye phantom by means of an electromagnetic navigation system.
Variable stiffness (VS) is an important feature that significantly enhances the dexterity of magnetic catheters used in minimally invasive surgeries. Existing magnetic catheters with VS consist of sensors, heaters, and tubular structures filled with low melting point alloys, which have a large stiffness change ratio but are toxic to humans. In this paper, a VS magnetic catheter is described for minimally invasive surgery; the catheter is based on a novel variable stiffness thread (VST), which is made of a conductive shape memory polymer (CSMP). The CSMP is nontoxic and simultaneously serves as a heater, a temperature sensor, and a VS substrate. The VST is made through a new scalable fabrication process, which consists of a dipping technique that enables the fabrication of threads with the desired electrical resistance and thickness (with a step size of 70 µm). Selective bending of a multisegmented VST catheter with a diameter of 2.0 mm under an external magnetic field of 20 mT is demonstrated. Compared to existing proof-of-concept VS catheters for cardiac ablation, each integrated VST segment has the lowest wall thickness of 0.75 mm and an outer diameter of 2.0 mm. The segment bends up to 51° and exhibits a stiffness change factor of 21.
Magnetic dipole-dipole interactions govern the behavior of magnetic matter across scales from micrometer colloidal particles to centimeter magnetic soft robots. This pairwise long-range interaction creates rich emergent phenomena under both static and dynamic magnetic fields. However, magnetic dipole particles, from either ferromagnetic or paramagnetic materials, tend to form chain-like structures as low-energy configurations due to dipole symmetry. The repulsion force between two magnetic dipoles raises challenges for creating stable magnetic assemblies with complex two-dimensional (2D) shapes. In this work, we propose a magnetic quadrupole module that is able to form stable and frustration-free magnetic assemblies with arbitrary 2D shapes. The quadrupole structure changes the magnetic particle-particle interaction in terms of both symmetry and strength. Each module has a tunable dipole moment that allows the magnetization of overall assemblies to be programmed at the single module level. We provide a simple combinatorial design method to reach both arbitrary shapes and arbitrary magnetizations concurrently. Last, by combining modules with soft segments, we demonstrate programmable actuation of magnetic metamaterials that could be used in applications for soft robots and electromagnetic metasurfaces.
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