No abstract

Purpose China was affected by an outbreak of coronavirus disease 2019 (COVID-19) in 2019–2020. Research data are needed to develop evidence-driven strategies to reduce the adverse psychological and occupational impacts on healthcare workers (HCWs). Methods From March 1, 2020, to March 8, 2020, 946 HCWs in China completed a survey consist of sociodemographic data, precautionary measures against COVID-19, and concerns about COVID-19. Self-administered questionnaire were collected to assess psychological and occupational adverse outcomes of HCWs. Multivariable logistic regression analysis was performed to identify factors associated with the outcomes. Results A total of 55.0%, 56.0% and 48.3% of the HCWs experienced burnout, psychological distress and posttraumatic stress, respectively. A total of seven factors were independently associated with burnout: good health status (OR 0.51, 95% CI 0.36–0.71), fear of contagion (OR 1.31, 95% CI 1.003–1.79), avoiding contact with children (OR 1.40, 95% CI 1.03–1.91), enough staff support at the workplace (OR 0.59, 95% CI 0.38–0.92), having to work overtime (OR 1.37, 95% CI 1.03–1.83), maladaptive coping (OR 3.28, 95% CI 2.42–4.45) and adaptive coping (OR 0.47, 95% CI 0.35–0.62). A total of 11 factors were independently associated with high psychological distress: having one child (OR 0.54, 95% CI 0.38–0.77), good health status (OR 0.57, 95% CI 0.39–0.83), alcohol abuse (OR 1.51, 95% CI 1.02–2.25), thinking the epidemic would continue for quite a long time (OR 1.59, 95% CI 1.08–2.34), wearing extra-work clothes (OR 1.51, 95% CI 1.06–2.15),effective protective equipment (OR 0.45, 95% CI 0.22–0.90), enough staff support at the workplace (OR 0.55, 95% CI 0.34–0.89), unable to take care of families (OR 1.99, 95% CI 1.42–2.78), economic losses (OR 1.62, 95% CI 1.14–2.31), maladaptive coping (OR 6.88, 95% CI 4.75–9.97),and adaptive coping (OR 0.29, 95% CI 0.21–0.41). These factors were independently associated with posttraumatic stress: living with the elderly (OR 1.46, 95% CI 1.04–2.05), alcohol abuse (OR 1.41, 95% CI 1.002–1.98), working at a 3A hospital(OR 0.66, 95% CI 0.49–0.88), acquaintances confirmed COVID-19 (OR 2.14, 95% CI 1.20–3.84), fear of contagion (OR 1.87, 95% CI 1.40–2.50), believing they would survive if infected (OR 0.63, 95% CI 0.46–0.86), self-disinfected after arriving home (OR 1.43, 95% CI 1.01–2.02), interpersonal isolation (OR 1.65, 95% CI 1.21–2.26), unable to take care of families (OR 1.41, 95% CI 1.05–1.88) and maladaptive coping (OR 3.09, 95% CI 2.32–4.11). Conclusion The variance in adverse outcomes was explained by the effect of various factors, which will help policymakers better prepare for subsequent potential outbreaks of COVID-19. Supplementary Information The online version contains supplementary material available at 10.1007/s00420-021-01657-3.

Objective: Several studies have suggested a probable association between benign paroxysmal positional vertigo (BPPV) and both reduction of bone mineral density (BMD) and serum vitamin D levels, but none of these studies have explored their findings by examining bone turnover markers (BTM) in male idiopathic BPPV patients. This study aimed to evaluate the relationship between BMD and serum 25-hydroxyvitamin D (25(OH) D), with the occurrence of BPPV along with the characteristics of bone metabolism in male idiopathic BPPV patients.Methods: This retrospective study comprised 60 male idiopathic BPPV patients and 92 age-matched healthy controls referred to Ningbo No.2 Hospital during the period of February 2016 to February 2018. All subjects' serum levels of 25(OH) D, bone formation marker amino-terminal propeptide of type I procollagen (PINP), and bone resorption marker β-isomerized carboxy-terminal telopeptide of type I collagen (β-CTX) were measured. BMD was determined by dual energy X-ray absorption at the lumbar spine and hip.Results: Among male patients with BPPV, the prevalence of BMD reduction was 35.0%, which was similar to that of 27.2% in healthy controls. There were significant differences in the mean serum 25(OH) D level and prevalence of vitamin D deficiency between the two groups, with p-values of 0.049 and 0.009, respectively. The bone turnover markers of PINP and β-CTX in BPPV patients were lower than those in healthy controls. Logistic regression showed that vitamin D deficiency were associated with BPPV with an odds ratio of 3.8 (95% confidence interval = 1.25–11.73).Conclusion: Our study found that decreased serum vitamin D may be a risk factor for BPPV in male patients. The level of bone turnover among male patients with BPPV was lower than that among healthy controls.