Nowadays, photodynamic therapy (PDT) is under the research spotlight as an appealing modality for various malignant tumors. Compared with conventional PDT treatment activated by ultraviolet or visible light, near infrared (NIR) light-triggered PDT possessing deeper penetration to lesion area and lower photodamage to normal tissue holds great potential for in vivo deep-seated tumor. In this review, recent research progress related to the exploration of NIR light responsive PDT nanosystems is summarized. To address current obstacles of PDT treatment and facilitate the effective utilization, several innovative strategies are developed and introduced into PDT nanosystems, including the conjugation with targeted moieties, O self-sufficient PDT, dual photosensitizers (PSs)-loaded PDT nanoplatform, and PDT-involved synergistic therapy. Finally, the potential challenges as well as the prospective for further development are also discussed.
Color-tunable carbon dots have been synthesized via a one pot hydrothermal synthesis and re-dispersed in dimethylformamide solution after purification. Structural and optical property characterizations indicate that the concentration-dependent photoluminescent properties can be ascribed to the existence of multi-emissive centers in the carbon dots from core states, edge states and surface states. Therefore, a multi-center fluorescent mechanism for the carbon dots has been proposed according to the preservation effect and inductive effect of the solvent. The emission wavelength of the carbon dots with different concentrations can be tuned from 585 to 514 nm under the fixed excitation of 420 nm blue light, and a warm white light-emitting diode with a CIE color coordinate at (0.42, 0.35) is fabricated on a InGaN blue chip emitting 420 nm blue light.
Single-ion conducting gel polymer electrolytes possess both unity lithium ion transference numbers (∼0.98) and high ionic conductivities (∼5.8 mS cm−1).
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