This paper focuses on the continuous control of the unmanned aerial vehicle (UAV) based on a deep reinforcement learning method for a large-scale 3D complex environment. The purpose is to make the UAV reach any target point from a certain starting point, and the flying height and speed are variable during navigation. In this work, we propose a deep reinforcement learning (DRL)-based method combined with human-in-the-loop, which allows the UAV to avoid obstacles automatically during flying. We design multiple reward functions based on the relevant domain knowledge to guide UAV navigation. The role of human-in-the-loop is to dynamically change the reward function of the UAV in different situations to suit the obstacle avoidance of the UAV better. We verify the success rate and average step size on urban, rural, and forest scenarios, and the experimental results show that the proposed method can reduce the training convergence time and improve the efficiency and accuracy of navigation tasks. The code is available on the website https://github.com/Monnalo/UAV navigation.
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