Background: Dengue protease is a two-component protease that is important for viral replication. Results: An unlinked protease complex containing the NS2B regulatory region and the NS3 protease domain was obtained.
Conclusion:The unlinked protease complex produces dispersed cross-peaks in NMR spectra and exists predominantly in a closed conformation in solution.Significance: This new construct will be a useful tool for drug discovery against the dengue virus.
Electrodeposition of SbTe thin films was investigated at room temperature, where amorphous deposits were obtained. The electrodeposition of Sb was found to be induced by Te, while the latter was not affected by the Sb. Detailed studies on this induced deposition were carried out by varying the Sb͑III͒ and Te͑IV͒ concentrations, pH, and agitation. The Sb deposition rate was found to be independent of the concentrations of both species but dependent on the pH and agitation. A phase transition from amorphous films into crystalline Sb 2 Te 3 at 120°C was observed for the plated SbTe.
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