Bone tissue engineering (BTE) is an optimized approach for bone regeneration to overcome the disadvantages of lacking donors. Biocompatibility, biodegradability, simulation of extracellular matrix (ECM), and excellent mechanical properties are essential characteristics of BTE scaffold, sometimes including drug loading capacity. Electrospinning is a simple technique to prepare fibrous scaffolds because of its efficiency, adaptability, and flexible preparation of electrospinning solution. Recent studies about electrospinning in BTE are summarized in this review. First, we summarized various types of polymers used in electrospinning and methods of electrospinning in recent work. Then, we divided them into three parts according to their main role in BTE, (1) ECM simulation, (2) mechanical support, and (3) drug delivery system.

No abstract

Approaches of optical microscopy (OM), scanning electron microscopy (SEM), X-ray diffraction, electron backscattered diffraction (EBSD), transmission electron microscopy (TEM) and mechanical property testing have been used to study the microstructure and mechanical properties of Mg-6.1Zn-0.7Zr alloys before and after equal channel angular pressing (ECAP) investigated in detail using. The study demonstrates that the microstructure comprises of fine-grained equiaxed dynamic recrystallization. The size of various grains is in the range 2.3-5.2 μm along the boundaries of unrecrystallized grains after 6 passes of ECAP. Meanwhile, the Mg-Zn and Mg-Zn-Zr compounds gradually crush into fine dispersed particles and the dislocation density increases. With increase of pass the average (0001)<11-20> basal slip Schmid factor gradually increases to 0.41. The strength and ductility have improved with increasing of ECAP pass. Notably, after 6 passes, due to decrease of grain size and the strengthening effects of fragmentized secondary phase particles, the ultimate tensile strength increases to 260 MPa, and the elongation at break exceeds 28.6%.

Sambucus javanica Blume. is a Chinese native medicinal plant with high medicinal value. In this study, the MaxEnt model was used to explore the relationship between the geographical distribution of S. javanica and environmental factors, and to construct the distribution pattern of S. javanica under different climate scenarios. The results showed that the environmental conditions suitable for the distribution of S. javanica were as follows: precipitation in June ranged from 156.36 mm to 383.25 mm; solar radiation in December ranged from 6750.00 kJ·m-2·day-1 to 10521.00 kJ·m-2·day-1; isothermality ranged from 24.06 to 35.50; precipitation of warmest quarter ranged from 447.92 mm to 825.00 mm. Among them, precipitation and temperature were the key environmental factors affecting the distribution patterns of S. javanica. This plant could grow well mainly in two regions in China, covering a total area of 2.73 × 106 km2. The first region mainly consists of Guizhou, western Hubei, southeastern Chongqing, southwestern Hunan, northern Guangxi, and a small part of eastern Yunnan. The second region mainly consists of Zhejiang, southern Anhui, and northern Fujian. Under the future SSP126 and SSP585 scenarios, potentially suitable habitats in the eastern part of the potential distribution of S. javanica (Jiangxi, Fujian, Zhejiang, and Anhui) might be at risk of habitat fragmentation. Based on the result of this study, Real-time monitoring of wild groups of S. javanica is now recommended to protect its genetic diversity. These findings are supposed to promote the effective conservation and utilization of S. javanica in the future.