Dermatoglyphic features are inherited by polygenic system with individual gene contributing a small additive effect. The present research aims to primarily study the various dermatoglyphic patterns in the patients of the Maturity Onset Diabetes Mellitus (Type II diabetes) and compare these statistically with the dermatoglyphic patterns in individuals not suffering from it. The present study was carried out on 101 (51 male and 50 female) clinically diagnosed patients of maturity onset diabetes mellitus. Healthy controls (n=100, 50 males and 50 females) were studied for comparison. Palmar prints were obtained in all the patients and controls and the dermatoglyphic patterns were analyzed using statistical considerations. Standard fingertip pattern configurations and landmarks were used in the study. Significantly higher frequency of arches and lower frequency of whorls were observed in female diabetics than controls. Dankmeijer's Index was highest in female diabetic group and Furuhata's Index was highest in the male control group. AFRC and TFRC were significantly lower in diabetic females than controls. Findings of the present study after a meticulous analysis of different fingertip dermatoglyphic variables highlights on the possible markers and indicate that there is scope for further study on a larger sample size.

Introduction: Muscular variations in the form of accessory muscles are common and observed during cadaveric dissections, surgeries or investigative radiological procedures. Knowledge of such variations in upper limb is useful for hand surgeons and neurosurgeons. Materials and Methods: Total 156 (80 of right side and 76 of left side) upper limbs of unknown sex were dissected for presence of accessory muscles in the flexor compartment of the forearm. Observed accessory bellies and anatomical variant muscles were studied for its origin and insertion, size and shape and its important relations. Observations: Accessory head for the flexor pollicis longus (ahFPL) was the most common variation found in 56 (36%) limbs. Accessory head for the flexor digitorum profundus (ahFDP) was observed in five (3.2%) limbs, and accessory head for the flexor digitorum superficialis (ahFDS) in two limbs (1.2%,). Two accessory bellies in the same hand with common or separate origin were found in 5 limbs (3.2%). An anatomical variant flexor carpi radialis brevis (FCRB), which is not very common, was found in one limb. Conclusion: Accessory bellies of the muscles in the forearm are known for compression neuropathies like anterior interosseous nerve syndrome (AINS). Available accessory muscles like FCRB could be used for tendon transfers in patients with arthritis of thumb. Awareness of such variations helps in diagnosis of neuropathies, to avoid complications during surgeries and most importantly accessory muscles could be used for tendon graft/ transfer to to transform disability into functional hands.

KOKAN region is characterized by undernutrition across all stages of lifecycle. Developmental Origins of Health & Disease hypothesis suggests that environmental influences in the early period of growth and development can contribute to the risks of noncommunicable diseases (NCD) in adulthood. Newborns and placentas of 815 pregnant mothers delivered in a rural hospital were studied. We tested the hypothesis that low placental weight will be associated with low birth weight (LBW). Mothers had a mean age of 26 years and were smaller in size at delivery [mean height of 152.1 cm (±6.1 cm), weight 52 kg (±10.2 kg), body mass index (BMI) 22.5 kg/m2 (±4.1 kg/m2)]. Mean placental weight was 488 g (±120 g). Mean birth weight, length, and head circumference of the newborn were 2.54 kg (±0.5 kg), 46.3 cm (±3.1 cm), and 32.7 cm (±1.7 cm), respectively. Prevalence of LBW, stunting, and small head size was 41.6%, 42.2%, and 18.2%, respectively. Maternal height, weight, and BMI at delivery were all positively associated with placental weight (p < 0.01 for all). Mothers with placentas in the lowest placental weight tertile had an increased likelihood of producing an LBW baby [OR 7.7, 95% CI (5.0, 11.8)], a stunted baby [OR 1.9 (1.4, 2.9)], or a baby with a small head circumference [OR 2.4 (1.4, 4.0)]. Mothers in the lowest height tertile had odds of producing a LBW baby [OR 1.8 95% CI (1.2, 2.7)] or a stunted baby [OR 1.6 (1.1, 2.3)]. There is a need to improve the nutritional status of women in KOKAN region which may reduce the risk of NCD.

Introduction:The TP53 gene is located on chromosome 17p13.1.P53 gene considered as the guardian of the genome belongs to a threemembered gene family p53, p63, and p73. 1 p53 plays a vital role in human cancer and whose mutation was observed in nearly 50% of cancer all around the world. In the present study, genotype distribution was assessed in 147 infertile males, fertile males, and the associations of TP53 Arg72Pro polymorphism with hormonal and seminal parameters were investigated. Materials and methods: A total of 147 infertility men and 150 fertile men were taken for the study. Polymerase chain reaction (PCR) was carried out to amplify the exon 4 of the human p53 CODON 72 genotyping was performed by restriction fragments length polymorphism (RFLP). Results: In summary, the AA genotype and the A allele are significantly associated with azoospermic men when compared to fertile men. Conclusion:The study found preliminary evidence demonstrated that the TP53 gene Arg72 Pro polymorphism contributes significant association to male infertility. Aim and objective: To analyze the association of p53 gene polymorphism in male infertility cases in the study population.

No abstract