Meningiomatosis (multiple meningioma) are defined by the presence of at least 2 simultaneous lesions present at different intracranial locations without an association with neurofibromatosis type 2. It accounts for 1-10 % of meningioma. it is usually common in females. It can occur with or without signs of neurofibromatosis. The primary goal of treatment is to remove the lesion causing sign and symptoms and to follow others. Surgery is the main treatment option as like solitary meningioma and the prognosis is usually very good. We will discuss here a case of 52 years female diagnosed as a case of multiple meningioma describe her clinical, radiological and histopathological features. We will also highlight the surgical managements and postoperative course.
Wolf-Hirschhorn syndrome (WHS) is caused by a chromosomal deletion of the band 4p16.3 with characteristic craniofacial features -'Greek warrior helmet' 5 facies (prominent glabella, hypertelorism, broad beaked nose and frontal bossing), high-arched eyebrows, protruding eyes, epicanthal folds, short philtrum, distinct mouth with downturned corners, micrognathia, dysplastic ears, preauricular tags. Till date there are very few case reports of Wolf-Hirschhorn syndrome.Here we report a case that had characteristic dysmorphic facies (Figure1) 'Greek warrior helmet' and was diagnosed as a case of WHS. But presence of Meningo-encephalocele and lissencephaly is rarely reported in literature in association with Wolf-hirschhorn syndrome till date.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.