Coronavirus disease 2019 (COVID-19) has been shown to impact multiple organs, even in instances where patients did not show any symptoms. In this case report, we detail a six-year-old male child presenting with focal seizures without an antecedent history of epilepsy. The child presented with twitching movements on the right side of the face involving the oral cavity. Non-contrast brain MRI showed meningoencephalitis. He was given antibiotics, antipyretics, and antiepileptic drugs (AEDs), but his clinical condition continued to deteriorate despite treatment. Oropharyngeal and nasopharyngeal swabs tested positive for COVID-19. Thus, treatment was initiated for COVID-19 encephalitis and seizures with intravenous immune globulin (IVIG) and steroids. Frequency of seizures decreased dramatically after steroids were initiated and remained infrequent during the five days of steroid therapy. After steroids were discontinued seizures returned but were shorter, less frequent and manageable with AEDs. The child was discharged on AEDs and was seizure-free at six months of follow-up. The following case report details the disease and treatment pathway of the patient.
Conditions that impact an individual's health are referred to as social determinants of health. Through a retrospective study (January 2017-February 2022) and statistical analysis, researchers looked at the relationship between social demands and type 2 diabetes mellitus (T2DM) diagnosis. All social demands, with the exception of childcare, were more typically documented in patients with T2DM. Prescription expense, conveyance, and health literacy were the domains with the greatest relationships. These results might help health systems and social service providers develop collaborations to help in certain areas.
Several Phase-III clinical studies investigating vaccine safety and effectiveness have been published a year following the first breakout of the COVID-19 pandemic. These vaccine candidates were produced using a variety of vaccination technologies, including mRNA, recombinant protein, adenoviral vector, and inactivated virus-based platforms, by various research organizations and pharmaceutical firms. Despite many successful clinical studies, participants are restricted by trial inclusion and exclusion criteria, geographic location, and the current state of the virus epidemic. Many concerns remain, particularly for specific populations such as the elderly, women who are pregnant or nursing, and teenagers. Vaccine effectiveness against asymptomatic infection and particular viral variations, on the other hand, is still largely unclear. This review will focus on vaccination candidates that have completed Phase-III clinical trials and will examine the scientific evidence that has been gathered so far for these vaccine candidates for various subgroups of individuals and virus variations.
Background: Globally every day, approximately 830 women die from preventable causes related to pregnancy and childbirth. 99% of all maternal deaths occur in developing countries. Care before during and after childbirth can save the lives of women and new born babies which is also known as birth preparedness and complication readiness (BPACR). The objective of this study aims to assess practice of birth preparedness and complication readiness among families of women in the field practicing area of Kamineni Academy of Medical Sciences and Research Centre, Hyderabad.Methods: Field based descriptive study was done during August 2019 to February 2020 for a period of 6 months in urban field practising area. Sample size was 450 families, which includes, antenatal mothers 450 and their husbands 450, and 220 reproductive age group women. Results: Awareness of key danger signs during pregnancy (73.8%), labour/childbirth (56.7%) and postpartum (44%) were more among antenatal women whereas knowledge of danger signs of new born was highest among husbands of currently pregnant women. Planning of giving birth with a skilled provider was also high among antenatal women (98%) and in their husbands (97.5%), but saving for the same was very low in reproductive age group study population (20.4%).Conclusions: All these findings conclude Indian husbands of urban were more concerned about problems and safety of their offspring that is new born, than antenatal mother. Awareness of danger signs in the new born was lowest.
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