Oral delivery of nanogels reduces gut inflammation.

Review presents the advances in design of biomaterials for gene therapy to mitigate the inflammatory bowel disease, and challenges associated with oral delivery of gene therapeutics.

Release of anticancer drugs in systemic circulation and their associated toxicity are responsible for poor efficacy of chemotherapy. Therefore, identification of new chemotherapeutic combinations designed to be released near the...

Proinflammatory cytokines like Tumor Necrosis Factor-α (TNF-α) are critical mediators of inflammatory bowel disease pathogenesis, and are important targets to restore intestinal homeostasis. Herein, we present the engineering and screening...