BACKGROUND Ocular adnexal lymphomas are mainly Non-Hodgkin's lymphomas distributed in the conjunctiva, orbit and eyelids. These lymphomas are the commonest of the ocular adnexal lymphoid proliferations. In this study, ten cases of ocular adnexal lymphomas were analysed over a three year period. MATERIALS AND METHODS Comparison of clinicopathologic and histomorphologic features was done in ten cases of ocular adnexal lymphomas Immunohistochemical confirmation was obtained in six cases. RESULTS Of ten cases, equal incidence (40% each) was found in conjunctiva and orbit with eyelid forming 20%. Most common presentation of intraocular lymphoma was found to be decreased vision with non-resolving uveitis. Orbital tumours presented as proptosis with visible conjunctival mass. The commonest histologic type of intraocular NHL is extra nodal marginal zone lymphoma (MALT lymphoma). Primary intraocular lymphomas are unilateral and 75% cases become bilateral with central nervous system involvement and death. CONCLUSION The present study is a retrospective analysis of ten cases of ocular adnexal lymphomas over a period of three years. Clinicopathologic and histomorphologic analysis was done in detail. Immunohistochemical confirmation was obtained in 6 cases.
BACKGROUND Though histopathology is the gold standard investigation for diagnosing most benign and malignant lesions of bone, the decalcification process required for removing bone hardness makes it a time-consuming process. Sediment cytology is a rapid investigative procedure utilising the cells in the specimen containers after proper fixation, processing and staining. The objective of this study was to compare the diagnostic efficacy of sediment cytology of bone lesions with the histopathology. METHODS The study was conducted in 50 samples of bony tissues received in the histopathology lab during the study time. The fixative fluid containing specimens were first agitated for procuring the cells from the sample. The sediment obtained was processed and stained as a cytology sample and studied under microscope. Based on cytology findings they were classified into benign, malignant, inflammatory and inconclusive. The specimen was processed as routine histopathologic sample and final diagnosis was made from it. RESULTS Sediment cytology of malignant bone lesions showed a very high specificity (100 %) but only a moderate sensitivity of 80 %. Sediment cytology of benign bone lesions also showed a higher specificity of 100 % but only a moderate sensitivity of 84.6 %. CONCLUSIONS If adequately cellular, biopsy sediment cytology is a simple, inexpensive, rapid tool for the early diagnosis of bone lesions. Sediment cytology can act as a good complementary test to histopathology. KEYWORDS Bone Lesions, Cytology, Sediment Cytology, Histopathology
BACKGROUND Immune Thrombocytopenic Purpura (ITP) is one of the most commonly encountered disease in paediatric practice. Thorough clinical and morphological study of peripheral blood and bone marrow is required for confirming ITP. Clinicomorphological aspects of paediatric ITP is a less studied topic especially in developing countries like India. The objective was to study the clinical and morphological profile of paediatric cases of ITP. METHODS This is a 5-year record based retrospective study conducted in a paediatric tertiary health care centre in Kerala, South India. Data of all paediatric cases diagnosed as ITP including clinical presentation, clinical findings, blood counts, peripheral blood morphology, bone marrow morphology, and treatment response was collected and entered in SPSS software version 16.0 and analysed. For assessing correlation, chi-square test was used. RESULTS The age of children ranged from 3 months to 15 years. H/o viral fever was noted in 53 % cases. Cases which had moderate and severe thrombocytopenia were 74 % and 21 % respectively. Isolated thrombocytopenia was the most common peripheral blood picture observed with few cases showing coexisting eosinophilia and anaemia. All cases showed megakaryocyte proliferation in marrow with 9 % cases showing coexisting iron deficiency anaemia. Majority of cases showed rapid response to steroid / IVIG therapy and the response had no correlation with grade of thrombocytopenia (p value < 0.05). CONCLUSIONS Paediatric cases of ITP usually present following viral infections or vaccination, with worrisome bleeding episodes, petechiae, ecchymosis or purpura. KEYWORDS ITP, Paediatrics, Platelet Count, Thrombocytopenia, Vaccination
The solitary brous tumour is a rare broblastic tumour which accounts for less than 2 % of soft tissue tumours and is associated with NAB2- STAT6 fusion [1]. It was originally described in pleura but has been reported in various anatomical sites. We report a case of solitary brous tumour in Para ovarian location. A 69-year-old female presented with a large abdominal mass which was initially thought to be a parasitic leiomyoma on MRI. The tumour was surgically removed and the diagnosis of a solitary brous tumour was conrmed on immunohistochemical analysis. Para ovarian location of the solitary brous tumour is rare, hence presenting this case.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.