Objective: The aim of our study was to assess the comparative patient satisfaction and side-effects of the currently prescribed drugs – tamsulosin and silodosin for benign prostatic hyperplasia (BPH). Methods: A prospective study was conducted in a total of 110 BPH patients from the Department of Urology for a period of 6 months. Fifty-five patients in each group received silodosin 8 mg or tamsulosin 0.4 mg once daily. Data were collected using a suitably designed pro forma and the patient satisfaction was assessed with patient’s perception of study medication (PPSM) scale. International prostate symptom score (IPSS) was used for assessing the severity of symptoms. Results: The current study found that the treatment had a significant effect on improving scores of PPSM and IPSS at which all changes were significant at p<0.01 (paired t-test). An independent t-test showed that silodosin group had a greater improvement in PPSM scores – PPSM total by 40.4%, PPSM global by 43.7%, and PPSM pain by 0.39% which was supported by corresponding decline in IPSS scores. The side effects reported for tamsulosin were headache (5.5%), dizziness (5.5%), dry mouth (3.6%), and postural hypotension (14.4%) and those reported for silodosin were myalgia (5.5%), dizziness (7.3%), diarrhea (1.8%), and postural hypotension (10.9%). Conclusion: Patient satisfaction was improved by both the alpha blockers but silodosin showed a significantly greater increase in patient satisfaction than tamsulosin. Thus, silodosin is the better drug of choice.
Background: Benign prostate hyperplasia (BPH) is one of the common bothersome diseases among elderly men of age greater than 50 years. The aim of the current study was to evaluate the impact of patient counselling on quality of life (QoL), knowledge, attitude and practice (KAP) and medication adherence among patients.Methods: A Prospective study was conducted in a total of 110 BPH patients from the department of urology for a period of 6 months. 55 patients in each group received silodosin 8 mg or tamsulosin 0.4 mg once daily. Data was collected by using a suitably designed proforma, international prostate symptom score (IPSS) and BPH impact index were used for assessing QoL, morisky green levin scale for medication adherence and a suitably designed KAP questionnaire for assessing KAP. Patients were counselled regarding the disease, drugs and lifestyle modifications using patient information leaflet.Results: The current study found that both the Tamsulosin and Silodosin group had an improvement on QoL, IPSS Q 8 by 36% and 41.5% respectively and improvement on BII by 35.5% and 47.3% respectively. Medication adherence had significant improvement from first to second review by 12%. Significant improvement in knowledge by 80.1%, attitude by 72.7% and practice by 79.2% were observed.Conclusions: The provision of effective counselling was found to have a profound impact on improving patient’s quality of life, medication adherence, knowledge, attitude and practice.
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