OBJECTIVE:The goal of this study is to predict the long term LV function in RV apical paced patients.
BACKGROUND:We have used the GLS measured by 2D STE, as a tool to predict the patients who are at high risk of
developing pacing induced LV dysfunction (PIVD) or pacing induced cardiomyopathy (PCMP).
METHOD: A prospective study conducted in the cardiology department of Government Rajaji Hospital, Madurai, including 47 patients of AV
block or sinus node dysfunction with preserved ejection fraction undergoing RV apical pacing. This study population was followed up with serial
trans thoracic 2D echocardiography with GLS by STE for a period of 12 months for the development of PIVD (PCMP).
RESULTS: Of the study population, 42.5% (n=20) developed PIVD at 12 months and these patients had a signicant fall in their GLS values at
one month post pacing. (GLS -16.94% vs -17.60%; p=0.02).
CONCLUSION: GLS, a novel echocardiographic parameter can be used as a tool in predicting the decline in ejection fraction following
pacemaker implantation with potential to predict the development of PIVD. GLS at one month post pacing had a high predictive accuracy for
identifying those who developed PIVD later in the follow up.
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